| 词条 | Clostebol acetate |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [(8R,9S,10R,13S,14S,17S)-4-Chloro-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate | image = Clostebol acetate.svg | width = 225px | image2 = Clostebol acetate molecule ball.png | width2 = 225px | tradename = Macrobin, Steranabol, Alfa-Trofodermin, Megagrisevit | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intramuscular injection | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 855-19-6 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 13327 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 12762 | UNII = 780ZZX4P14 | KEGG = | ChEBI = 81712 | ChEMBL = 519327 | C= 21 | H= 29 | Cl=1 | O= 3 | SMILES = CC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=C(C(=O)CC[C@]34C)Cl)C | StdInChI_Ref = | StdInChI = 1S/C21H29ClO3/c1-12(23)25-18-7-6-14-13-4-5-16-19(22)17(24)9-11-20(16,2)15(13)8-10-21(14,18)3/h13-15,18H,4-11H2,1-3H3/t13-,14-,15-,18-,20+,21-/m0/s1 | StdInChIKey_Ref = | StdInChIKey = XYGMEFJSKQEBTO-KUJXMBTLSA-N | synonyms = NSC-72159 }}Clostebol acetate (BAN) (brand names Macrobin, Steranabol, Alfa-Trofodermin, Megagrisevit), also known as 4-chlorotestosterone 17β-acetate (4-CLTA) or as 4-chloroandrost-4-en-17β-ol-3-one 17β-acetate, is a synthetic, injected anabolic-androgenic steroid (AAS) and a derivative of testosterone that is marketed in Germany and Italy.[1][2][3] It is an androgen ester – specifically, the C17β acetate ester of clostebol (4-chlorotestosterone) – and acts as a prodrug of clostebol in the body.[1][2]{{Additional citation needed|date=November 2016}} Clostebol acetate is administered via intramuscular injection.[3][4] See also
References1. ^1 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA305|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=305–}} {{Androgens and antiandrogens}}{{Androgen receptor modulators}}{{steroid-stub}}{{genito-urinary-drug-stub}}2. ^1 {{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA265|date=January 2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=265–}} 3. ^1 {{cite book|author1=I.K. Morton|author2=Judith M. Hall|title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=mqaOMOtk61IC&pg=PA80|date=31 October 1999|publisher=Springer Science & Business Media|isbn=978-0-7514-0499-9|pages=80–}} 4. ^{{cite book|author1=Mutschler|author2=Hartmut Derendorf|title=Drug Actions: Basic Principles and Theraputic Aspects|url=https://books.google.com/books?id=IvN4mZxraMkC&pg=PA304|year=1995|publisher=CRC Press|isbn=978-0-8493-7774-7|pages=304–}} 7 : Acetate esters|Androgen esters|Androgens and anabolic steroids|Androstanes|Organochlorides|Prodrugs|World Anti-Doping Agency prohibited substances |
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