| 词条 | Cloxotestosterone acetate |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [2,2,2-trichloro-1-[[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]oxy]ethyl] acetate | image = Cloxotestosterone acetate.svg | width = 250px | image2 = Cloxotestosterone acetate molecule ball.png | width2 = 250px | tradename = Caprosem | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intramuscular injection | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 13867-82-8 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 20056698 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 16739648 | UNII = 2X9YIP66ZO | KEGG = | ChEBI = | ChEMBL = | synonyms = Testosterone 17β-chloral hemiacetal O-acetate; 17β-(1-(Acetyloxy)-2,2,2-trichloroethoxy)androst-4-en-3-one | C=23 | H=31 | Cl=3 | O=4 | molecular_weight = 477.847 g/mol | SMILES = CC(=O)OC(C(Cl)(Cl)Cl)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C | StdInChI_Ref = | StdInChI = 1S/C23H31Cl3O4/c1-13(27)29-20(23(24,25)26)30-19-7-6-17-16-5-4-14-12-15(28)8-10-21(14,2)18(16)9-11-22(17,19)3/h12,16-20H,4-11H2,1-3H3/t16-,17-,18-,19-,20?,21-,22-/m0/s1 | StdInChIKey_Ref = | StdInChIKey = SJWGVEPLFJGWNB-UWSXKFMVSA-N }}Cloxotestosterone acetate ({{abbrlink|INN|International Nonproprietary Name}}; brand name Caprosem), also known as testosterone 17β-chloral hemiacetal O-acetate, is a synthetic, injected anabolic–androgenic steroid (AAS) and an androgen ether and ester – specifically, the O-acetate ester of cloxotestosterone, the 17β-trichloro hemiacetal ether of testosterone.[1] It is administered via intramuscular injection as a 100 mg, 2 mL aqueous suspension and lasts 4 to 6 weeks with a single administration.[2] The drug was first marketed in the early 1960s.[2] See also
References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA641|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=641–}} {{Androgens and antiandrogens}}{{Androgen receptor modulators}}{{steroid-stub}}{{genito-urinary-drug-stub}}2. ^1 Advertisements. Proceedings of the Royal Society of Medicine. 1963;56(1):21. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1896961/pdf/procrsmed00225-0002.pdf 7 : Acetate esters|Androgens and anabolic steroids|Androstanes|Ethers|Organochlorides|Prodrugs|Testosterone esters |
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