| 词条 | CM156 |
| 释义 |
| IUPAC_name = 3-[4-(4-cyclohexylpiperazin-1-yl)butyl]-1,3-benzothiazole-2-thione | image = CM156.png | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = | ATC_prefix = | ATC_suffix = | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | PubChem = 17756659 | ChemSpiderID = 23325411 | UNII = | C=21 | H=31 | N=3 | S=2 | molecular_weight = 389.62 g/mol | smiles = c1ccc2c(c1)n(c(=S)s2)CCCCN3CCN(CC3)C4CCCCC4 | StdInChI = 1S/C21H31N3S2/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2 | StdInChIKey = FJGOTAJCEJCFEV-UHFFFAOYSA-N }} CM156[1] is a piperazine based chemical compound with nanomolar affinity for both sigma receptor subtypes that has been shown to counteract the deleterious effects of administered cocaine. See also
References1. ^{{cite journal|last1=Xu|first1=Y. T.|last2=Kaushal|first2=N.|last3=Shaikh|first3=J.|last4=Wilson|first4=L. L.|last5=Mesangeau|first5=C.|last6=McCurdy|first6=C. R.|last7=Matsumoto|first7=R. R.|title=A Novel Substituted Piperazine, CM156, Attenuates the Stimulant and Toxic Effects of Cocaine in Mice|journal=Journal of Pharmacology and Experimental Therapeutics|volume=333|issue=2|year=2010|pages=491–500|issn=0022-3565|doi=10.1124/jpet.109.161398|pmid=20100904|pmc=2872963}} {{Sigma receptor modulators}}{{nervous-system-drug-stub}} 1 : Piperazines |
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