| 释义 |
- Function
- References
- Further reading
{{Infobox_gene}}CKLF like MARVEL transmembrane domain containing 3 is a protein that in humans is encoded by the CMTM3 gene. [1]FunctionThis gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]. References 1. ^{{cite web| title = Entrez Gene: CKLF like MARVEL transmembrane domain containing 3| url = https://www.ncbi.nlm.nih.gov/gene/123920| accessdate = 2018-01-05}}
Further reading {{refbegin | 2}}- {{cite journal |vauthors=Han W, Ding P, Xu M, Wang L, Rui M, Shi S, Liu Y, Zheng Y, Chen Y, Yang T, Ma D |title=Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation |journal=Genomics |volume=81 |issue=6 |pages=609–17 |year=2003 |pmid=12782130 |doi= |url=}}
- {{cite journal |vauthors=Zhong J, Wang Y, Qiu X, Mo X, Liu Y, Li T, Song Q, Ma D, Han W |title=Characterization and expression profile of CMTM3/CKLFSF3 |journal=J. Biochem. Mol. Biol. |volume=39 |issue=5 |pages=537–45 |year=2006 |pmid=17002874 |doi= |url=}}
- {{cite journal |vauthors=Wang Y, Li T, Qiu X, Mo X, Zhang Y, Song Q, Ma D, Han W |title=CMTM3 can affect the transcription activity of androgen receptor and inhibit the expression level of PSA in LNCaP cells |journal=Biochem. Biophys. Res. Commun. |volume=371 |issue=1 |pages=54–8 |year=2008 |pmid=18402773 |doi=10.1016/j.bbrc.2008.03.143 |url=}}
- {{cite journal |vauthors=Xie J, Yuan Y, Liu Z, Xiao Y, Zhang X, Qin C, Sheng Z, Xu T, Wang X |title=CMTM3 is frequently reduced in clear cell renal cell carcinoma and exhibits tumor suppressor activities |journal=Clin Transl Oncol |volume=16 |issue=4 |pages=402–9 |year=2014 |pmid=23907292 |doi=10.1007/s12094-013-1092-3 |url=}}
- {{cite journal |vauthors=Su Y, Lin Y, Zhang L, Liu B, Yuan W, Mo X, Wang X, Li H, Xing X, Cheng X, Dong B, Hu Y, Du H, Zhu Y, Ding N, Li J, Liu W, Ma Y, Qiu X, Ji J, Han W |title=CMTM3 inhibits cell migration and invasion and correlates with favorable prognosis in gastric cancer |journal=Cancer Sci. |volume=105 |issue=1 |pages=26–34 |year=2014 |pmid=24131472 |pmc=4317871 |doi=10.1111/cas.12304 |url=}}
- {{cite journal |vauthors=Delic S, Thuy A, Schulze M, Proescholdt MA, Dietrich P, Bosserhoff AK, Riemenschneider MJ |title=Systematic investigation of CMTM family genes suggests relevance to glioblastoma pathogenesis and CMTM1 and CMTM3 as priority targets |journal=Genes Chromosomes Cancer |volume=54 |issue=7 |pages=433–43 |year=2015 |pmid=25931111 |doi=10.1002/gcc.22255 |url=}}
- {{cite journal |vauthors=Zhang H, Zhang J, Nan X, Li X, Qu J, Hong Y, Sun L, Chen Y, Li T |title=CMTM3 inhibits cell growth and migration and predicts favorable survival in oral squamous cell carcinoma |journal=Tumour Biol. |volume=36 |issue=10 |pages=7849–58 |year=2015 |pmid=25946973 |doi=10.1007/s13277-015-3504-1 |url=}}
- {{cite journal |vauthors=Hu F, Yuan W, Wang X, Sheng Z, Yuan Y, Qin C, He C, Xu T |title=CMTM3 is reduced in prostate cancer and inhibits migration, invasion and growth of LNCaP cells |journal=Clin Transl Oncol |volume=17 |issue=8 |pages=632–9 |year=2015 |pmid=25990505 |doi=10.1007/s12094-015-1288-9 |url=}}
- {{cite journal |vauthors=Yuan W, Li T, Mo X, Wang X, Liu B, Wang W, Su Y, Xu L, Han W |title=Knockdown of CMTM3 promotes metastasis of gastric cancer via the STAT3/Twist1/EMT signaling pathway |journal=Oncotarget |volume=7 |issue=20 |pages=29507–19 |year=2016 |pmid=27121055 |pmc=5045413 |doi=10.18632/oncotarget.8789 |url=}}
{{refend}}{{NLM content}}{{gene-16-stub}} |