| 词条 | COG2827 RNA motif |
| 释义 |
| Name = COG2827 | image = RF02938.svg | width = | caption = Consensus secondary structure and sequence conservation of COG2827 RNA | Symbol = COG2827 | AltSymbols = | Rfam = RF02938 | miRBase = | miRBase_family = | RNA_type = Gene; sRNA | Tax_domain = | GO = | SO = {{SO|0001263}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} The COG2827 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] COG2827 motifs are found in Clostridiales. It is ambiguous whether COG2827 RNAs function as cis-regulatory elements or whether they operate in trans. Most COG2827 RNAs occur upstream of genes encoding GIY-YIG endonucleases. Although these genes are often located inside self-splicing introns, the COG2827 RNA motif is much smaller and simpler than known self-splicing introns, and is therefore unlikely to function as a ribozyme. References1. ^{{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811-10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 |url=}} 1 : Non-coding RNA |
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