| 释义 |
- Function
- References
- Further reading
{{Infobox_gene}}Copine 3 is a protein that in humans is encoded by the CPNE3 gene. [1]FunctionCalcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a protein which contains two type II C2 domains in the amino-terminus and an A domain-like sequence in the carboxy-terminus. The A domain mediates interactions between integrins and extracellular ligands. [provided by RefSeq, Aug 2008]. References 1. ^{{cite web| title = Entrez Gene: Copine 3| url = https://www.ncbi.nlm.nih.gov/gene/8895| accessdate = 2018-01-16}}
Further reading {{refbegin | 2}}- {{cite journal |vauthors=Thomas G, Jacobs KB, Yeager M, Kraft P, Wacholder S, Orr N, Yu K, Chatterjee N, Welch R, Hutchinson A, Crenshaw A, Cancel-Tassin G, Staats BJ, Wang Z, Gonzalez-Bosquet J, Fang J, Deng X, Berndt SI, Calle EE, Feigelson HS, Thun MJ, Rodriguez C, Albanes D, Virtamo J, Weinstein S, Schumacher FR, Giovannucci E, Willett WC, Cussenot O, Valeri A, Andriole GL, Crawford ED, Tucker M, Gerhard DS, Fraumeni JF, Hoover R, Hayes RB, Hunter DJ, Chanock SJ |title=Multiple loci identified in a genome-wide association study of prostate cancer |journal=Nat. Genet. |volume=40 |issue=3 |pages=310–5 |year=2008 |pmid=18264096 |doi=10.1038/ng.91 |url=}}
- {{cite journal |vauthors=Thomas G, Jacobs KB, Yeager M, Kraft P, Wacholder S, Orr N, Yu K, Chatterjee N, Welch R, Hutchinson A, Crenshaw A, Cancel-Tassin G, Staats BJ, Wang Z, Gonzalez-Bosquet J, Fang J, Deng X, Berndt SI, Calle EE, Feigelson HS, Thun MJ, Rodriguez C, Albanes D, Virtamo J, Weinstein S, Schumacher FR, Giovannucci E, Willett WC, Cussenot O, Valeri A, Andriole GL, Crawford ED, Tucker M, Gerhard DS, Fraumeni JF, Hoover R, Hayes RB, Hunter DJ, Chanock SJ |title=Multiple loci identified in a genome-wide association study of prostate cancer |journal=Nat. Genet. |volume=40 |issue=3 |pages=310–5 |year=2008 |pmid=18264096 |doi=10.1038/ng.91 |url=}}
- {{cite journal |vauthors=Heinrich C, Keller C, Boulay A, Vecchi M, Bianchi M, Sack R, Lienhard S, Duss S, Hofsteenge J, Hynes NE |title=Copine-III interacts with ErbB2 and promotes tumor cell migration |journal=Oncogene |volume=29 |issue=11 |pages=1598–610 |year=2010 |pmid=20010870 |doi=10.1038/onc.2009.456 |url=}}
- {{cite journal |vauthors=Cohen OS, Mccoy SY, Middleton FA, Bialosuknia S, Zhang-James Y, Liu L, Tsuang MT, Faraone SV, Glatt SJ |title=Transcriptomic analysis of postmortem brain identifies dysregulated splicing events in novel candidate genes for schizophrenia |journal=Schizophr. Res. |volume=142 |issue=1-3 |pages=188–99 |year=2012 |pmid=23062752 |pmc=3502694 |doi=10.1016/j.schres.2012.09.015 |url=}}
- {{cite journal |vauthors=Lin HC, Zhang FL, Geng Q, Yu T, Cui YQ, Liu XH, Li J, Yan MX, Liu L, He XH, Li JJ, Yao M |title=Quantitative proteomic analysis identifies CPNE3 as a novel metastasis-promoting gene in NSCLC |journal=J. Proteome Res. |volume=12 |issue=7 |pages=3423–33 |year=2013 |pmid=23713811 |doi=10.1021/pr400273z |url=}}
- {{cite journal |vauthors=Choi HY, Park N, Na JB, Ko ES, Park JY, Yoo JC |title=Direct binding of Copine3 with Jab1 activates downstream ErbB2 signaling and motility in SKBr3 breast cancer cells |journal=Oncol. Rep. |volume=35 |issue=2 |pages=1147–52 |year=2016 |pmid=26719032 |doi=10.3892/or.2015.4472 |url=}}
{{refend}}{{gene-8-stub}}{{NLM content}} |