| 词条 | Creative Biolabs |
| 释义 |
| name = Creative Biolabs, Inc. | logo = | logo_size = 246 px | logo_caption = | image = | type = corporation | industry = Biotechnology | genre = | owner = | num_employees = | parent = | divisions = | subsid = | footnotes = | vector_logo = | foundation = 2005 | location_country = USA | location = 45-1 Ramsey Road, Shirley, New York 11967 | company_slogan = | homepage = | dissolved = }} Creative Biolabs, Inc. is a life-science company which produces and supplies biotech products and services for early drug discovery and development, including various phage display libraries[1] such as pre-made libraries,[2] phage display services,[3][4] antibody sequencing,[5] and antibody humanization.[6] Customers include pharmaceutical companies, academic institutions, government agencies, clinical research organizations and biotechnology companies. HistoryCreative Biolabs Inc. was founded in 2005 by a group of scientists researching on the treatment and prevention of intractable diseases like cancer. The company has distributors in Australia, New Zealand, Japan and other countries in Europe, Asia, and America. Its headquarter is in Shirley, New York.[7] In June 2016, Creative Biolabs set up its first scholarship program.[8] ServicesFab construction[9] is a complex technique as Fab fragments contain both variable domains and constant regions. The same heavy and light variable chains used for scFv construction can be used in the construction of Fab. Construction of pre-made phage display libraries. Pre-made phage display library[10] is a laboratory technique for the study of protein–protein, protein–peptide, and protein–DNA interactions that uses bacteriophages (viruses that infect bacteria) to connect proteins with the genetic information that encodes them. Sequencing services[11] such as Database Assisted Shotgun Sequencing (DASS) technology Analysis of microarray hybridization data[12] Yeast two-hybrid screen[13] ProductsMonoclonal antibodies such as mouse anti-human Duox2 monoclonal antibody S-40[14] Immunoglobulin Y (IgY) such as Anti-ADP3 chicken IgY[15]Antibody libraries such as HuSdLTM phage display human single domain antibody library[16] References1. ^{{Cite web|url=http://www.pr.com/press-release/512637|title=Creative Biolabs Works with UEC for Commercial Phage Display Technology|website=PR.com|access-date=2017-05-18}} 2. ^{{Cite journal|title= Practical Tips for Construction of Custom Peptide Libraries and Affinity Selection by Using Commercially Available Phage Display Cloning Systems| pmc=3444042 | pmid=22991651 | doi=10.1155/2012/295719| volume=2012| journal=J Nucleic Acids| page=295719 | last1 = Fukunaga | first1 = K | last2 = Taki | first2 = M| year=2012 }} 3. ^{{Cite web|url=http://www.biospace.com/News/creative-biolabs-announced-phage-display/442795|title=Creative Biolabs Announced Phage Display Technology For Anti-membrane Protein Antibody Production|website=BioSpace|access-date=2017-05-18}} 4. ^{{Cite web|url=http://markets.ask.com/ask/news/read/33123649|title=Creative Biolabs Announces A Successful Completion Of Virbac's Unique Monoclonal Antibody Discovery Project Through Cooperation With In-Cell-Art|website=ASK |access-date=2017-05-18}} 5. ^{{Cite web|url=http://www.prweb.com/releases/2015/04/prweb12651813.htm|title=Creative Biolabs Introduces Innovative Antibody Sequencing Service with DASS Technology for Quicker Testing and Guaranteed Results|website=PRWeb |access-date=2017-05-18}} 6. ^{{Cite web|url=http://www.einpresswire.com/article/280130721/creative-biolabs-updates-its-antibody-humanization-service-to-further-accelerate-your-monoclonal-antibody-research|title=Creative Biolabs Updates Its Antibody Humanization Service to Further Accelerate Your Monoclonal Antibody Research|website=EIN Presswire|access-date=2017-05-18}} 7. ^{{Cite web|url= https://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapId=183064699|title= Company Overview of Creative Biolabs Inc.|website= Bloomberg|access-date=2017-05-18}} 8. ^{{Cite web|url= http://thenode.biologists.com/event/creative-biolabs-scholarship-program|title= Creative Biolabs Scholarship Program|website=The Company of Biologists|access-date=2017-05-18}} 9. ^{{Cite journal|last=Wanczyk|first=Heather|last2=Barker|first2=Tolga|last3=Rood|first3=Debra|last4=Zapata|first4=Daniel I.|last5=Howell|first5=Amy R.|last6=Richardson|first6=Stewart K.|last7=Zinckgraf|first7=John|last8=Marusov|first8=Gregory P.|last9=Lynes|first9=Michael A.|date=2013-03-19|title=Cloning and Characterization of a Hybridoma Secreting a 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-Specific Monoclonal Antibody and Recombinant F(ab)|journal=Toxins|volume=5|issue=3|pages=568–589|doi=10.3390/toxins5030568|issn=2072-6651|pmc=3705279|pmid=23518474}} 10. ^{{Citation|title=Glycopeptides and methods of making and using them|date=Oct 13, 2015|url=http://www.google.com/patents/US9156906|inventor-last=Franco|inventor-first=Alessandra|issue=US9156906 B2|accessdate=2017-07-12}} 11. ^{{Cite journal|last=Hammerberg|first=Bruce|last2=Eguiluz-Hernandez|first2=Sitka|date=2017-02-01|title=Therapeutic anti-IgE monoclonal antibody single chain variable fragment (scFv) safety and immunomodulatory effects after one time injection in four dogs|journal=Veterinary Dermatology|language=en|volume=28|issue=1|pages=52–e13|doi=10.1111/vde.12354|pmid=27426720|issn=1365-3164}} 12. ^{{Cite journal|last=Gass|first=Justin T.|last2=Olive|first2=M. Foster|date=2008-04-28|title=Transcriptional profiling of the rat frontal cortex following administration of the mGlu5 antagonists MPEP and MTEP|journal=European Journal of Pharmacology|volume=584|issue=2–3|pages=253–262|doi=10.1016/j.ejphar.2008.02.032|issn=0014-2999|pmc=2386089|pmid=18346726}} 13. ^{{Cite journal|last=Horgan|first=Conor P.|last2=Hanscom|first2=Sara R.|last3=Kelly|first3=Eoin E.|last4=McCaffrey|first4=Mary W.|date=2012-02-14|title=Tumor Susceptibility Gene 101 (TSG101) Is a Novel Binding-Partner for the Class II Rab11-FIPs|journal=PLoS ONE|volume=7|issue=2|doi=10.1371/journal.pone.0032030|issn=1932-6203|pmc=3279423|pmid=22348143|page=e32030}} 14. ^{{Cite journal|last=Wu|first=Yongzhong|last2=Antony|first2=Smitha|last3=Juhasz|first3=Agnes|last4=Lu|first4=Jiamo|last5=Ge|first5=Yun|last6=Jiang|first6=Guojian|last7=Roy|first7=Krishnendu|last8=Doroshow|first8=James H.|date=2011-04-08|title=Up-regulation and Sustained Activation of Stat1 Are Essential for Interferon-γ (IFN-γ)-induced Dual Oxidase 2 (Duox2) and Dual Oxidase A2 (DuoxA2) Expression in Human Pancreatic Cancer Cell Lines|journal=The Journal of Biological Chemistry|volume=286|issue=14|pages=12245–12256|doi=10.1074/jbc.M110.191031|issn=0021-9258|pmc=3069428|pmid=21321110}} 15. ^{{Cite journal|last=Morimoto|first=Jumpei|last2=Sarkar|first2=Mohosin|last3=Kenrick|first3=Sophia|last4=Kodadek|first4=Thomas|date=2014-08-20|title=Dextran as a Generally Applicable Multivalent Scaffold for Improving Immunoglobulin-Binding Affinities of Peptide and Peptidomimetic Ligands|journal=Bioconjugate Chemistry|volume=25|issue=8|pages=1479–1491|doi=10.1021/bc500226j|issn=1043-1802|pmc=4140544|pmid=25073654}} 16. ^{{Cite journal|last=Ma|first=Lin|last2=Gu|first2=Kai|last3=Zhang|first3=Cheng-hai|last4=Chen|first4=Xue-tao|last5=Jiang|first5=Yi|last6=Melcher|first6=Karsten|last7=Zhang|first7=Juan|last8=Wang|first8=Min|last9=Xu|first9=H Eric|date=June 2016|title=Generation and characterization of a human nanobody against VEGFR-2|journal=Acta Pharmacologica Sinica|volume=37|issue=6|pages=857–864|doi=10.1038/aps.2016.2|issn=1671-4083|pmc=4954766|pmid=27108602}} 4 : Companies based in Suffolk County, New York|Biotechnology companies of the United States|Biotechnology companies established in 2005|2005 establishments in New York (state) |
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