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词条 Cynthia Larive
释义

  1. Education and career

  2. Research

  3. Awards

  4. References

{{Infobox scientist
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| name = Cynthia Larive
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| nationality = American
| fields = bioanalytical chemistry
| workplaces = {{ublist|University of Kansas|University of California, Riverside}}
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| alma_mater = {{ublist|South Dakota State University, B.S,|Purdue University, M.S.|{{nowrap|University of California, Riverside, Ph.D.}}}}
| thesis_title = NMR studies of neurohypophyseal peptide hormones
| thesis_url = https://search.proquest.com/docview/303984253/
| thesis_year = 1992
| doctoral_advisor = Dallas L. Rabenstein
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Cynthia Larive is an American bioanalytical chemist known for developing new instrumentation and analysis techniques involving nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry. She is currently a professor of chemistry and Provost and Executive Vice Chancellor at the University of California, Riverside. She is a fellow of AAAS, IUPAC and ACS, Associate Editor for the ACS journal Analytical Chemistry and editor of the Analytical Sciences Digital Library.

Education and career

Larive received her bachelor of science from South Dakota State University in 1980, her masters of science degree from Purdue University in 1982, and a Ph.D. from the University of California, Riverside, in 1992.[1][2][3]

Initially she was a professor in the chemistry department at the University of Kansas, and later joined the faculty of the University of California, Riverside, in 2005.[2] Since 2004 she has served as the editor-in-chief of the Analytical Sciences Digital Library.[4]

In February 2017, Larive was appointed interim provost and executive vice chancellor for University of California, Riverside, and the appointment was made permanent in October.[5]

Research

Larive works in the field of bioanalytical chemistry, applying analytical tools such as nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry to the products of chemical separations. Much of her research focuses on reducing the amount of sample needed for analysis, such as constructing microcoil NMR probes that can measure as little as 25 nL of sample and are usable as part of an capillary isotachophoresis apparatus. This has been applied to structure determination of heparin and heparan sulfate.[1][6] She developed NMR pulse sequences to study protein ligand interactions in complexes with multiple ligands.[1][7] She also researches analytical methods for metabolomics[1][8] and chemogenomics for the reaction of plants to pesticides and hypoxia using NMR and mass spectroscopy.[1]

NMR is often thought of as a low-sensitivity method, but Larive's laboratory has developed ways of increasing the sensitivity of their measurements to obtain precise chemical and structural information.[9] The techniques she is developing are relevant to understanding carbohydrate structure and biosynthesis, designing new drugs and measuring the purity of pharmaceuticals.[10] Her work in developing chemical profiles for substances also has relevance for the authentication of foodstuffs such as wine, olive oil, and pomegranate juice.[11]

Awards

Larive has received a number of awards, including the National Science Foundation CAREER Award in 1995.[12]

She received the American Chemical Society Analytical Division's J. Calvin Giddings Award for Excellence in Education in 2007[13] and served as chair of the Analytical Division in 2013. In 2015, Larive received the Award for Volunteer Service to the American Chemical Society.[4] In 2018, the Analytical Chemistry Division of the American Chemical Society honored Larive with the Award for Distinguished Service to the Field of Analytical Chemistry.

Larive is a Fellow of the American Association for the Advancement of Science (AAAS) (2008),[14] the International Union of Pure and Applied Chemistry (IUPAC) (2004) and the American Chemical Society (ACS) (2011).[15]

References

1. ^{{Cite web |url=http://chem.ucr.edu/faculty.html?id=13 |title=Department of Chemistry: Faculty |website=chem.ucr.edu |access-date=2016-03-20 |author=}}
2. ^{{Cite book |title=American Men & Women of Science |last=Nemeh |first=Katherine H. |publisher=Gale, Cengage Learning |year=2008 |issn=0000-1287 |oclc=231724858 |location=Farmington Hills, MI |pages=690}}
3. ^{{cite thesis |url=https://search.proquest.com/docview/303984253/ |title=NMR studies of neurohypophyseal peptide hormones |date=1992 |publisher=University of California, Riverside |type=Ph.D. |last=Larive |first=Cynthia K. |via=ProQuest |subscription=yes |oclc=28833337}}
4. ^{{Cite journal |url=http://cen.acs.org/articles/92/web/2014/06/Volunteer-Service-Award-Cynthia-Larive.html |title=Volunteer Service Award To Cynthia Larive |journal=Chemical & Engineering News |last=Ainsworth|first=Susan J. |access-date=2016-03-20}}
5. ^{{cite web |url=https://ucrtoday.ucr.edu/49547 |title=Cynthia K. Larive Named as UCR Provost |work=UCR Today |first=J.D. |last=Warren |date=October 24, 2017}}
6. ^{{cite journal |last1=Korir |first1=AK |last2=Larive |first2=CK |title=On-line NMR detection of microgram quantities of heparin-derived oligosaccharides and their structure elucidation by microcoil NMR. |journal=Analytical and Bioanalytical Chemistry |date=August 2007 |volume=388 |issue=8 |pages=1707–16 |pmid=17607565 |doi=10.1007/s00216-007-1400-2}}
7. ^{{cite journal |last1=Otto |first1=WH |last2=Larive |first2=CK |title=Improved spin-echo-edited NMR diffusion measurements. |journal=Journal of Magnetic Resonance |date=December 2001 |volume=153 |issue=2 |pages=273–6 |pmid=11740906 |url=http://www.sciencedirect.com/science/article/pii/S1090780701924449 |accessdate=23 March 2016 |doi=10.1006/jmre.2001.2444|bibcode=2001JMagR.153..273O }}
8. ^{{cite journal |last1=Larive |first1=Cynthia K. |last2=Barding |first2=Gregory A. |last3=Dinges |first3=Meredith M. |title=NMR Spectroscopy for Metabolomics and Metabolic Profiling |journal=Analytical Chemistry |date=6 January 2015 |volume=87 |issue=1 |pages=133–146 |doi=10.1021/ac504075g |pmid=25375201 }}
9. ^{{cite book |editor-last1=Yan |editor-first1=Bing |title=Analysis and purification methods in combinatorial chemistry |date=2004 |publisher=Wiley-Interscience |location=Hoboken (N.J.) |isbn=978-0-471-26929-8 |page=3 |oclc=54360519}}
10. ^{{cite web |title=Award Abstract #1213845 Enhancing the NMR Characterization of Amino Sugars |url=https://www.nsf.gov/awardsearch/showAward?AWD_ID=1213845&HistoricalAwards=false |archive-url=https://web.archive.org/web/20160402184734/https://www.nsf.gov/awardsearch/showAward?AWD_ID=1213845&HistoricalAwards=false |dead-url=yes |archive-date=2 April 2016 |website=National Science Foundation |accessdate=21 March 2016}}
11. ^{{cite journal |title=Chemist Tests Pomegranate Juice Authenticity |journal=Food Quality and Safety |date=December 30, 2010 |url=http://www.foodqualityandsafety.com/article/chemist-tests-pomegranate-juice-authenticity/ |accessdate=21 March 2016 |author=}}
12. ^{{cite journal|title=IV. Accomplishments, Breakthroughs |journal=EPSCoR Newsletter |date=1995 |volume=1 |issue=2 |url=https://www.nsf.gov/pubs/stis1995/lehr9502/lehr9502.txt |accessdate=21 March 2016 |deadurl=yes |archiveurl=https://web.archive.org/web/20130413074744/http://nsf.gov/pubs/stis1995/lehr9502/lehr9502.txt |archivedate=April 13, 2013 }}
13. ^{{cite news |title=UCR Chemist Recognized by the American Chemical Society |url=http://newsroom.ucr.edu/1553 |accessdate=21 March 2016 |work=UCR News |date=April 10, 2007 |author=}}
14. ^{{cite web |title=Thirteen UCR Faculty Members Recognized by the American Association for the Advancement of Science |url=http://newsroom.ucr.edu/1987 |website=University of California, Riverside |accessdate=21 March 2016 |date=December 18, 2008 |author=}}
15. ^{{cite news |title=Cindy Larive receives Award for Volunteer Service to the American Chemical Society |work=ACS - DAC Division Newsletter |date=February 2, 2016 |pages=7 |url=http://www.analyticalsciences.org/currentNewsletter.pdf |accessdate=21 March 2016 |author=}}
{{authority control}}{{DEFAULTSORT:Larive, Cynthia}}

14 : Analytical chemists|Year of birth missing (living people)|Living people|Women chemists|American women scientists|Fellows of the American Chemical Society|Fellows of the American Association for the Advancement of Science|University of California, Riverside faculty|University of Kansas faculty|University of California, Riverside alumni|South Dakota State University alumni|Purdue University alumni|21st-century American chemists|21st-century women scientists

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