| 词条 | Dacryoscintigraphy |
| 释义 |
| name = Dacryoscintigraphy | image = Lacrimal Scintigraphy.png | alt = | caption = | pronounce = | synonyms = microscintigraphy nuclear dacryocystogram nuclear lacrimal scan lacrimal scintillography | DiseasesDB = | ICD10 = {{ICD10PCS|C8191ZZ}} | ICD9 = | ICDO = | MedlinePlus = | eMedicine = | MeshID = | OPS301 = | LOINC = {{LOINC|39670-5}} | reference_range = }} Dacryoscintigraphy (DSG), also known as lacrimal scintigraphy, is a nuclear medicine technique for imaging the lacrimal apparatus. It is used to identify obstructions, for example in the lacrimal duct, nasal cavity or nasolacrimal duct. ProcedureThe typical procedure involves use of Technetium-99m colloid, or in some cases pertechnetate. The colloid is prepared with an activity of approximately 20 megabecquerels in 1 millilitre (ml). Patients place their head in a support and chin rest and a single drop of 0.01 ml is delivered to each eye. Imaging with a gamma camera commences immediately, with a number of images acquired over 15 minutes.[1] Clinical applicationsTypical indications include epiphora and dacryocystitis.[2] DSG allows quantification of tear turnover and drainage.[3] Various quantification models have been developed, which must account for the variable drainage of asymptomatic systems.[4] Some drugs administered to the eye via eye drops, such as beta blockers for glaucoma, can be hazardous if quickly drained and absorbed through the nasolacrimal duct. DSG is considered the best method to quantitatively assess the proportion of the dose drained in this way.[5] It can also be useful in assessing functional problems, where the lacrimal system appears unobstructed, and for post-operative progress.[6][7] Advantages of DSG over dacrocystography include better functional information and a lack of injection.[8] DSG does not provide precise localisation and may not be useful in cases of complete obstruction.[9] HistoryThe technique was first introduced in 1972.[10] References1. ^{{cite web|title=Clinical Guidelines for Lacrimal Scintigraphy|url=http://www.bnms.org.uk/images/Lacrimal_Scintigraphy_2016.pdf|website=BNMS|accessdate=23 May 2017|date=April 2013}} {{Medical imaging|state=collapsed}}2. ^{{cite book|last1=Prakash|first1=Dibya|title=Nuclear Medicine: A Guide for Healthcare Professionals and Patients|publisher=Springer Science & Business Media|isbn=9788132218265|page=81|url=https://books.google.com/books?id=FH5WAwAAQBAJ&pg=PA81|language=en}} 3. ^{{cite journal|last1=Detorakis|first1=EfstathiosT|last2=Zissimopoulos|first2=Athanassios|last3=Ioannakis|first3=Konstantinos|last4=Kozobolis|first4=VassiliosP|title=Lacrimal Outflow Mechanisms and the Role of Scintigraphy: Current Trends|journal=World Journal of Nuclear Medicine|date=2014|volume=13|issue=1|page=16|doi=10.4103/1450-1147.138569|pmc=4149763}} 4. ^{{cite journal|last1=Tomlinson|first1=Alan|last2=Khanal|first2=Santosh|title=Assessment of Tear Film Dynamics: Quantification Approach|journal=The Ocular Surface|date=April 2005|volume=3|issue=2|pages=81–95|doi=10.1016/S1542-0124(12)70157-X|pmid=17131012}} 5. ^{{cite journal|last1=Wilson|first1=Clive G|title=Assessing ocular drug delivery with lachrimal scintigraphy|journal=Pharmaceutical Science & Technology Today|date=August 1999|volume=2|issue=8|pages=321–326|doi=10.1016/S1461-5347(99)00176-5|pmid=10441276}} 6. ^{{cite journal|last1=Chan|first1=WengOnn|last2=Malhotra|first2=Raman|last3=Kakizaki|first3=Hirohiko|last4=Leibovitch|first4=Igal|last5=Selva|first5=Dinesh|title=Perspective: what does the term functional mean in the context of epiphora?|journal=Clinical & Experimental Ophthalmology|date=September 2012|volume=40|issue=7|pages=749–754|doi=10.1111/j.1442-9071.2012.02791.x|pmid=22429759}} 7. ^{{cite journal|last1=Lefebvre|first1=Daniel R.|last2=Freitag|first2=Suzanne K.|title=Update on Imaging of the Lacrimal Drainage System|journal=Seminars in Ophthalmology|date=19 November 2012|volume=27|issue=5-6|pages=175–186|doi=10.3109/08820538.2012.711413}} 8. ^{{cite book|last1=Bennett|first1=Paige A.|last2=Oza|first2=Umesh D.|title=Diagnostic Imaging: Nuclear Medicine E-Book|publisher=Elsevier Health Sciences|isbn=9780323400442|page=304|url=https://books.google.com/books?id=4tWZCwAAQBAJ&pg=PA304|language=en}} 9. ^{{cite journal|last1=Sagili|first1=Suresh|last2=Selva|first2=Dinesh|last3=Malhotra|first3=Raman|title=Lacrimal Scintigraphy: “Interpretation More Art than Science”|journal=Orbit|date=10 April 2012|volume=31|issue=2|pages=77–85|doi=10.3109/01676830.2011.648797|pmid=22489850}} 10. ^{{cite journal|last1=Rossomondo|first1=R. M.|last2=Carlton|first2=W. H.|last3=Trueblood|first3=J. H.|last4=Thomas|first4=R. P.|title=A New Method of Evaluating Lacrimal Drainage|journal=Archives of Ophthalmology|date=1 November 1972|volume=88|issue=5|pages=523–525|doi=10.1001/archopht.1972.01000030525010|pmid=4634791}} 2 : 2d nuclear medical imaging|Eye procedures |
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