词条 | Daniel Voytas |
释义 |
| name = Daniel Voytas, Ph.D. | image = File:DanVoytas-sq.png | image_size = 250 px | alt = | caption = | birth_date = | birth_place = | death_date = | death_place = | resting_place = | resting_place_coordinates = | residence = | citizenship = | nationality = | fields = Biology | workplaces = University of Minnesota, Calyxt | alma_mater = Harvard Medical School | doctoral_advisor = | academic_advisors = | doctoral_students = | notable_students = | known_for = genome engineering technologies | author_abbrev_bot = | author_abbrev_zoo = | influences = | influenced = | awards = | signature = | signature_alt = | footnotes = | spouse = }} Daniel Voytas, Ph.D., is Professor of Genetics, Cell Biology and Development at the University of Minnesota and Director of the Center for Precision Plant Genomics. He is also the Chief Scientific Officer of Calyxt, an agricultural biotechnology company focused on developing crops that provide consumer benefit. BiographyDan earned a Ph.D. in genetics from Harvard Medical School under the supervision of Frederick M. Ausubel. His graduate work focused on studying transposable elements in plants. Dan then worked as a postdoctoral fellow at Johns Hopkins with Jef Boeke; his work focused on several retrotransposons in yeast and helped clarify the molecular mechanisms by which retrotransposons select chromosomal integration sites. In 1992, Dan joined the faculty at Iowa State University. He was promoted to Associate Professor in 1997 and to Professor in 2001. In 2008, he joined the faculty in the Department of Genetics, Cell Biology and Development at the University of Minnesota. Dan is best known for his pioneering work to develop methods for precisely altering DNA sequences in living cells, enabling detailed functional analysis of genes and genetic pathways. Dan's work has enabled efficient methods for targeted genome modification of plants using sequence-specific nucleases. Using zinc finger nucleases (ZFNs), TAL effector nucleases (TALEN), and the CRISPR/Cas9 system, Dan has achieved targeted gene knockouts, replacements and insertions in a variety of plant species. This type of targeted genome modification has applications ranging from understanding plant gene function to developing crop plants with new traits of value. His current work is focused on optimizing delivery of nucleases and donor DNA molecules to plant cells to more efficiently achieve targeted genetic alterations. RecognitionDan has co-authored over 100 peer-reviewed publications and holds a number of patents relating to genome editing and plant biotechnology. Dan is an elected Fellow of the American Association for the Advancement of Science.[1] The use of genetic engineering to modify crop plants was selected as one of MIT's 10 breakthrough technologies for the year 2015.[2] Selected publications
References1. ^{{Cite web|title = AAAS - The World's Largest General Scientific Society|url = http://www.aaas.org/|website = AAAS - The World's Largest General Scientific Society|accessdate = 2015-12-01}} 2. ^{{Cite web|title = Speeding Plant Growth to Feed the World {{!}} MIT Technology Review|url = http://www.technologyreview.com/featuredstory/535011/supercharged-photosynthesis/|website = MIT Technology Review|accessdate = 2015-12-01}} External links
5 : University of Minnesota faculty|American geneticists|Harvard Medical School alumni|Living people|Year of birth missing (living people) |
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