词条 | Diethylstilbestrol diacetate |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = (3E)-3-Hexene-3,4-diyldi-4,1-phenylene diacetate | image = Diethylstilbestrol diacetate.svg | width = | tradename = Hormostilboral Stark | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 5965-06-0 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 2297470 | UNII = | KEGG = | ChEBI = | ChEMBL = | C=22 | H=24 | O=4 | molecular_weight = 352.429 g/mol | smiles = CC\\C(=C(\\CC)C1=CC=C(OC(C)=O)C=C1)C1=CC=C(OC(C)=O)C=C1 | StdInChI_Ref = | StdInChI = 1S/C22H24O4/c1-5-21(17-7-11-19(12-8-17)25-15(3)23)22(6-2)18-9-13-20(14-10-18)26-16(4)24/h7-14H,5-6H2,1-4H3/b22-21+ | StdInChIKey_Ref = | StdInChIKey = NFCAKXYIMSRNLP-QURGRASLSA-N | synonyms = }}Diethylstilbestrol diacetate (DESDA) (brand name Hormostilboral Stark) is a synthetic, nonsteroidal estrogen of the stilbestrol group and an ester of diethylstilbestrol (DES) that was introduced for clinical use in the 1940s and was formerly marketed but is now no longer available.[1][2] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA396|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=396}} {{Estrogens and antiestrogens}}{{Estrogen receptor modulators}}{{genito-urinary-drug-stub}}2. ^{{cite journal | vauthors = SOLMSSEN UV | title = Synthetic estrogens and the relation between their structure and their activity | journal = Chem. Rev. | volume = 37 | issue = | pages = 481–598 | year = 1945 | pmid = 21013428 | doi = 10.1021/cr60118a004| url = }} 3 : Acetate esters|Estrogen esters|Synthetic estrogens |
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