| 词条 | Diethylstilbestrol dilaurate |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = 4-[(3E)-4-[4-(Dodecanoyloxy)phenyl]hex-3-en-3-yl]phenyl dodecanoate | image = Diethylstilbestrol dilaurate.svg | width = 250 | tradename = Acnestrol-Lotion | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = | UNII = | KEGG = | ChEBI = | ChEMBL = | C=42 | H=64 | O=4 | molecular_weight = 632.965 g/mol | smiles = CCCCCCCCCCCC(=O)OC1=CC=C(C=C1)C(\\CC)=C(/CC)C1=CC=C(OC(=O)CCCCCCCCCCC)C=C1 | StdInChI_Ref = | StdInChI = 1S/C42H64O4/c1-5-9-11-13-15-17-19-21-23-25-41(43)45-37-31-27-35(28-32-37)39(7-3)40(8-4)36-29-33-38(34-30-36)46-42(44)26-24-22-20-18-16-14-12-10-6-2/h27-34H,5-26H2,1-4H3/b40-39+ | StdInChIKey_Ref = | StdInChIKey = GEWSRLGHTICJOA-XQQUEIPISA-N | synonyms = }}Diethylstilbestrol dilaurate (brand name Acnestrol-Lotion) is a synthetic, nonsteroidal estrogen of the stilbestrol group and an ester of diethylstilbestrol (DES) that was previously marketed but is now no longer available.[1][2] It was formulated and used as a micronized topical medication to treat acne in adolescent boys and young men.[2][3] The drug was marketed as early as 1951.[4] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA397|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=397}} {{Estrogens and antiestrogens}}{{Estrogen receptor modulators}}{{genito-urinary-drug-stub}}2. ^1 {{cite book|author=Canadian Pharmaceutical Association|title=Compendium of pharmaceutical specialties (Canada) 1963|url=https://books.google.com/books?id=mflsAAAAMAAJ|year=1963|publisher=Canadian Pharmaceutical Association|page=14}} 3. ^{{cite book|author=Samuel B. Frank|title=Acne Vulgaris|url=https://books.google.com/books?id=FulsAAAAMAAJ|year=1971|publisher=Thomas|page=259}} 4. ^{{cite book|title=New York State Journal of Medicine|url=https://books.google.com/books?id=f7RYAAAAYAAJ|date=April 1951|publisher=Medical Society of the State of New York|page=1313}} 5 : Carboxylate esters|Estrogen esters|Phenols|Synthetic estrogens|Laurates |
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