| 词条 | Diethylstilbestrol dipalmitate |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [4-[(E)-4-(4-Hexadecanoyloxyphenyl)hex-3-en-3-yl]phenyl] hexadecanoate | image = Diethylstilbestrol dipalmitate.svg | width = | tradename = Palmestril, Stilpalmitate | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 6533-53-5 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 3034511 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 2298951 | UNII = 86291XW83U | KEGG = | ChEBI = | ChEMBL = | C=50 | H=80 | O=4 | molecular_weight = 745.180 g/mol | smiles = CCCCCCCCCCCCCCCC(=O)OC1=CC=C(C=C1)/C(=C(\\CC)/C2=CC=C(C=C2)OC(=O)CCCCCCCCCCCCCCC)/CC | StdInChI_Ref = | StdInChI = 1S/C50H80O4/c1-5-9-11-13-15-17-19-21-23-25-27-29-31-33-49(51)53-45-39-35-43(36-40-45)47(7-3)48(8-4)44-37-41-46(42-38-44)54-50(52)34-32-30-28-26-24-22-20-18-16-14-12-10-6-2/h35-42H,5-34H2,1-4H3/b48-47+ | StdInChIKey_Ref = | StdInChIKey = JUHYOIKJCUMOSQ-QJGAVIKSSA-N | synonyms = Stilpalmitate }}Diethylstilbestrol dipalmitate (brand names Palmestril, Stilpalmitate), also known as stilpalmitate, is a synthetic, nonsteroidal estrogen of the stilbestrol group and an ester of diethylstilbestrol (DES) that was formerly marketed but is now no longer available.[1][2] Its actions and uses are essentially the same as those of DES, but it is absorbed more slowly and for this reason has a longer duration of action and improved tolerability in comparison.[3] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA397|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=397}} {{Estrogens and antiestrogens}}{{Estrogen receptor modulators}}{{genito-urinary-drug-stub}}2. ^{{cite journal | vauthors = Hammes B, Laitman CJ | title = Diethylstilbestrol (DES) update: recommendations for the identification and management of DES-exposed individuals | journal = J Midwifery Womens Health | volume = 48 | issue = 1 | pages = 19–29 | year = 2003 | pmid = 12589302 | doi = 10.1016/s1526-9523(02)00370-7| url = }} 3. ^{{cite book|title=N.A.R.D. Journal ...: The Official Organ of the National Association of Retail Druggists|url=https://books.google.com/books?id=XfAjAQAAMAAJ|year=1948|publisher=National Association of Retail Druggists.|page=62}} 4 : Carboxylate esters|Estrogen esters|Phenols|Synthetic estrogens |
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