| 词条 | Diethylstilbestrol dipropionate |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [4-[(E)-4-(4-propanoyloxyphenyl)hex-3-en-3-yl]phenyl] propanoate | image = Diethylstilbestrol dipropionate.svg | width = 225px | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intramuscular injection | class = Nonsteroidal estrogen; Estrogen ester | synonyms = DESDP; Diethylstilbestrol dipropanoate; Stilboestrol dipropionate; Stilbestrol dipropionate | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 130-80-3 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | PubChem = 657220 | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 571380 | UNII = Y98CK3J0OL | C=24 | H=28 | O=4 | SMILES = CCC(=O)Oc1ccc(cc1)\\C(CC)=C(/CC)c2ccc(OC(=O)CC)cc2 | StdInChI_Ref = | StdInChI = 1S/C24H28O4/c1-5-21(17-9-13-19(14-10-17)27-23(25)7-3)22(6-2)18-11-15-20(16-12-18)28-24(26)8-4/h9-16H,5-8H2,1-4H3/b22-21+ | StdInChIKey_Ref = | StdInChIKey = VZMLEMYJUIIHNF-QURGRASLSA-N }}Diethylstilbestrol dipropionate (DESDP) (brand names Agostilben, Biokeral, Clinestrol, Cyclen, Estilbin, Estril, Neobenzoestrol, Orestol, Oroestrol, Ostregenin, Prostilbene, Stilbestriol DP, Stilboestrolum Dipropionicum, Stilboestrol, Synestrin, Willestrol, others), or diethylstilbestrol dipropanoate, also known as stilboestrol dipropionate ({{abbrlink|BANM|British Approved Name}}), is a synthetic nonsteroidal estrogen of the stilbestrol group that was formerly marketed widely throughout Europe.[1][2] It is an ester of diethylstilbestrol with propionic acid,[1] and is more slowly absorbed in the body than diethylstilbestrol.[3] The medication has been said to be one of the most potent estrogens known.[4]{{Oral potencies of estrogens}}{{Parenteral potencies and durations of estrogens}} See also
References1. ^1 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=RA1-PA129|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=397}} {{Estrogens and antiestrogens}}{{Estrogen receptor modulators}}{{Genito-urinary-drug-stub}}2. ^{{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA332|date=January 2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=332–}} 3. ^{{cite book|author1=Charles Owens Wilson|author2=Ole Gisvold|title=Organic Chemistry in Pharmacy|url=https://books.google.com/books?id=08_QAAAAMAAJ|year=1949|publisher=J. B. Lippincott|page=168}} 4. ^{{cite book|author=G. Dallenbach-Hellweg|title=Histopathology of the Endometrium|url=https://books.google.com/books?id=WaS1BwAAQBAJ&pg=PA200|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-3-642-96249-3|pages=200–}} 5 : Carboxylate esters|Estrogen esters|Estrogens|Phenols|Stilbenoids |
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