| 词条 | Dimethyldienolone |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = | image = Dimethyldienolone.svg | width = | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | class = Androgen; Anabolic steroid | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = | UNII = | KEGG = | ChEBI = | ChEMBL = | synonyms = RU-2788; 7α,17α-Dimethyldienolone; Δ9-Mibolerone; δ9-7α,17α-Dimethyl-19-nortestosterone; 7α,17α-Dimethylestr-4,9-dien-17β-ol-3-one | C= 20 | H= 28| O= 2 | molecular_weight = | SMILES = O([H])[C@](C)1CC[C@]([H])2[C@@]([H])3[C@](C)CC4=CC(CCC4=C3CC[C@@]21C)=O | StdInChI_Ref = | StdInChI = 1S/C20H27O2/c1-12-10-13-11-14(21)4-5-15(13)16-6-8-19(2)17(18(12)16)7-9-20(19,3)22/h11,17-18,22H,4-10H2,1-3H3/t17-,18+,19-,20-/m0/s1 | StdInChIKey_Ref = | StdInChIKey = IMHVOBKUZQVUFU-YRPNKDGESA-N }}Dimethyldienolone (developmental code name RU-2788), or 7α,17α-dimethyldienolone, also known as δ9-7α,17α-dimethyl-19-nortestosterone or as 7α,17α-dimethylestr-4,9-dien-17β-ol-3-one, is a 17α-alkylated androgen/anabolic steroid of the 19-nortestosterone group which was never marketed.[1][2] It is closely related to dimethyltrienolone, as well as to mibolerone and metribolone.[1][2] Dimethyldienolone shows high affinity for the androgen and progesterone receptors.[1][2] See also
References1. ^1 2 {{cite journal | vauthors = Delettré J, Mornon JP, Lepicard G, Ojasoo T, Raynaud JP | title = Steroid flexibility and receptor specificity | journal = J. Steroid Biochem. | volume = 13 | issue = 1 | pages = 45–59 | date = January 1980 | pmid = 7382482 | doi = 10.1016/0022-4731(80)90112-0 | url = }} {{Androgen receptor modulators}}{{Progesterone receptor modulators}}{{Steroid-stub}}{{Genito-urinary-drug-stub}}2. ^1 2 {{cite journal | vauthors = Ojasoo T, Delettré J, Mornon JP, Turpin-VanDycke C, Raynaud JP | title = Towards the mapping of the progesterone and androgen receptors | journal = J. Steroid Biochem. | volume = 27 | issue = 1-3 | pages = 255–69 | date = 1987 | pmid = 3695484 | doi = 10.1016/0022-4731(87)90317-7 | url = }} 7 : Alcohols|Androgens and anabolic steroids|Dienes|Estranes|Hepatotoxins|Ketones|Progestogens |
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