词条 | Draft:The Isis Thesis |
释义 |
The Isis Thesis is a.... The Isis Thesis (2004) by Judy Kay King is a semiotic study of ancient Egyptian funerary literature, art, ritual and architecture that decodes the genetic-evolutionary process that may make genetic control and biochemical longevity possible. The broad study spans from circa 2520 to 664 BCE and examines scholarly English translations of the least-corrupted Egyptian funerary texts and artwork carved on the Old Kingdom pyramid walls (Pyramid Texts) and the Middle Kingdom coffins of the nobility (Coffin Texts). The study also examines the Middle Kingdom Book of Two Ways, as well as New Kingdom texts such as the Book Amduat, the Book of Gates, the Egyptian Book of the Dead, the Theban Recension, and the Third Intermediate Period carvings on the subterranean walls of the Edifice of Pharaoh Taharqa at Karnak. The author argues that the unified themes and artwork are biological signs, describing the horizontal gene transfer (HGT) and postmortem evolution of the deceased pharaoh’s DNA via the dynamics of Escherichia coli's (E. coli) ancient fermentation metabolism (SOS response, lactose fermentation) and bacteriophage (phage for short) Lambda’s genetic switch to lysis (cloning or viral replication). The semiotic study is named after the Egyptian milk-goddess Isis, a genetic sign (DNA, genes, proteins) of lactose fermentation.[1]OverviewIn 2000, Judy Kay King left her teaching position to begin a full-time three-year independent study of the least-corrupted ancient Egyptian funerary texts.[2][3] Her interpretation of the Egyptian sign-system reveals that the pharaonic priesthood had a detailed knowledge about the ancient lactose fermentation metabolism of Escherichia coli (E. coli) bacterium interconnected to the genetic circuit of its bacterial virus Lambda, since their deities represent the functions of the necessary genes and proteins involved in the metabolic process. Both E.coli and phage Lambda inhabit the human gut or gastrointestinal tract, and phage Lambda is a well-studied gene vector or ferryboat for horizontal gene transfer (exchange of DNA between species). The Isis Thesis, a semiotic study of the corpus of Egyptian funerary texts, supports that horizontal gene transfer by phage Lambda allows the transfer of human genes to E. coli's microbial metabolism that switches on at human death for evolution. In other words, gut microbes and their metabolism not only influenced human genetic evolution, but also Egyptian cultural behavior, such as ritual, literature, art, and architecture, as well as their psychology. The author presented the Isis Thesis to an international Humanities audience in 2005,[4][5][6] as well as an international Egyptological audience in 2006.[7][8][9] Since the 2004 introductory study, the author has consistently expanded on the original research base by using a continuing methodology from 2004 to 2019 that incorporates new scientific research, while questioning the thesis inductively and deductively through the author’s international paper presentations, Semiotic Society of America paper presentations at annual conferences,[10][11][12][13] the writing of related books,[14][15] published peer-reviewed articles,[16][17][18][19][20][21] and a peer-reviewed article in The International Journal of Interdisciplinary Cultural Studies that is forthcoming in 2019.[22] Initial Experimental StudiesAlthough the negative medical association of viruses and bacteria as pathogens causing human disease persists[23], initial experimental studies appeared around 2010, showing that gut microbes influence the human brain and behavior[24] [25] [26] [27] [28] [29] [30] [31] [32]. In light of recent findings, an editorial in the journal Nature on February 7, 2019, supports a change in perspective: {{block indent |1=Just ten years ago, the idea that microorganisms in the human gut could influence the brain was often dismissed as wild. Not any more. Links between the central nervous system and the trillions of bacteria in the gut—the microbiota—are now a major focus of research, public interest and press coverage. But how does this ‘gut-brain axis’ work? The mechanisms by which microorganisms shape aspects of brain functioning such as memory and social behaviour, and how they might contribute to conditions such as depression and neurodegenerative disease, are tenuous and often controversial. . . . At least now, answering these questions is a wise pursuit, not a wild one.[33]}}Since 2004 when The Isis Thesis was published, researchers in the scientific community have introduced experimental evidence showing that gut microbes do influence human behavior.[34] In addition, an initial study by microbiologists, who analyzed the thanatomicrobiome (Greek: Thanatos “death”) in blood and internal organ tissues of 11 human cadavers, reveals that anaerobic (without oxygen) bacteria, such as Lactobacillus and E. coli that can ferment lactose, predominate with short postmortem intervals.[35] Another initial study showed that lack of oxygen causes a shift from aerobic to anaerobic fermentation at human death.[36] Researchers also studied the thanatotranscriptone in two vertebrate species (mouse and zebrafish), finding abundant gene transcripts for embryonic development, stress, immunity, inflammation, apoptosis, solute/ion/protein transport, epigenetic regulation, and cancer that switch on after organismal death.[37] Gene transcript abundances have been detected in three organisms (zebrafish, mouse, human), since Gonzalez-Herrera and co-workers (2013) found upregulated genes in 30 human cadavers.[38] Fulfilling the logic or science behind the Isis Thesis, experimental results confirm several of its expectations, since these initial studies show gut microbes influence human behavior, gut microbes predominate after death that can ferment lactose (fermentation occurs after human death), and various gene transcripts switch on in human cadavers. The Isis Thesis is also in agreement with contemporary research,[39] supporting that the lactose fermentation metabolism of E. coli interconnected to the genetic circuit of bacteriophage Lambda switches on when DNA damage activates E. coli’s SOS response that causes prophage reactivation and induction of lysis in Lambda phage. What is unexplored by biologists is the Isis Thesis expectation that horizontal gene transfer (the exchange of DNA between species) by bacteriophage Lambda can occur, allowing postmortem transformation of human DNA in an E. coli cell to produce something new. However, the following is known:
Initial studies[46] [47] [48] on the bidirectional gut microbiota-brain axis show that gut microbes communicate through the central nervous system to the human brain, influencing cognitive function, memory, social behavior, and even mental health, while producing the necessary neurotransmitters for the brain.[49] [50] [51] [52] [53] [54] These initial studies support the logic or science behind the Isis Thesis, as well as the author’s continuing argument that microbial metabolism allows emergent evolution and influences memory, consciousness, the unconscious, and social behavior, such as religion, myth and major cultural inventions.[55] [56] MethodologyThe methodology explained in The Isis Thesis (2004) details and analyzes themes in the least-corrupted Old Kingdom Pyramid Texts carved in the pyramids and the Middle Kingdom Coffin Texts carved in the wooden tombs of the nobility. This analysis produced 108 idea strands or repetitive literary themes, showing the underlying thematic unity of these least-corrupted texts. From these 108 idea strands, the author selected 30 key themes and then developed 26 matrices that translate Egyptian signs into possible scientific parallels. Through the development of 26 matrices of signs, the study shows that six additional funerary texts from the Middle Kingdom (Book of Two Ways), New Kingdom (Amduat, Book of Gates, Book of the Dead, Theban Recension) and Third Intermediate Period (wall carvings from Edifice of Taharqa) also support the interpretation of signs derived from the major Idea Strands in the least-corrupted Old Kingdom Pyramid Texts and Middle Kingdom Coffin Texts. These texts cover a period of time from circa 2520 BCE to 664 BCE. Artwork, imagery, and explanatory diagrams support the analysis, along with 318 scholarly book and peer-reviewed article citations, defining the possibility of postmortem evolution for humans via a bacterial metabolism interconnected to a viral genetic circuit. The abstract for King's article "Biosemiotics in Ancient Egyptian Texts: The Key Unlocking the Universal Secret of Sexuality and the Birth of the Limitless" (2006) presented at the Second International Congress for Young Egyptologists states: {{block indent |1=The initial methodology included multiple reviews of the least corrupted Pyramid and Coffin Texts to categorize 108 key themes that were synthesized into 30 major idea strands, defining textual events and activities of major deities. From this analysis, a hypothetical biological model of primary signs emerged for further testing in six additional texts: Amduat, Book of Gates, Book of Two Ways, Edifice of Taharqa, Papyrus of Ani including the Theban Recension. Abductive reasoning allowed modifications to the working model with verification of Egyptian principles supported by modern scientific research. A logical, holistic matrix emerged, explaining horizontal gene transfer as an option for afterlife transformation, while comparing these events to the macrocosmic processes in the solar wind/earth spin system. On the quantum level of DNA transcription, the texts depict and describe proteins binding, folding and tunneling, using modern terms and images to explain black hole/white hole formation/evaporation processes. Thus, they translate a DNA wormhole into a quantum mechanical Einstein-Rosen bridge back to the Early Universe . . .}}In the article "The Order of the Harmonious Whole" (2009),[57] King also uses a continuing inductive methodology for further research, based on the logic of Charles Sanders Peirce: {{block indent |1=Using Peircean logic on ancient documents, this paper is part of a continuing inductive argument (King 2005; 2006; 2007; 2007a; 2007b; 2008), testing predictions based on the thesis that the semiotic phenomenology of the pharaonic priesthood harbors an eschatological survival message for humans, viz., horizontal gene transfer (HGT) mediated by the complex bacteriophage Lambda. First, numerous textual analyses resulted in the abduction that Egyptian deities represent viral and bacterial proteins. Second, the activities of the deities or proteins (the union of the deceased king and the Sun-god, the dying/rising god Osiris, the brother rivalry between Seth and Horus, Isis’ virgin birth of the Horus child, and so on) model HGT and phage Lambda‘s complex lifestyles. Third, Lambda‘s lifestyles mirror most religious and mythic themes. Fourth, human genome research proves that viruses and bacteria have made us what we are today, and HGT is possible with our cell-type, suggesting that HGT may be possible at human death because DNA degrades into tiny fragments that can survive and be transported by a gene vector such as the very abundant phage Lambda. Fifth, space physics and microbiology research reinforces that earth and its magnetosphere operate like a bacterial cell. The holographic pharaonic perspective is that what is above is what is below; our classical cosmos emerges from the quantum formalism. Sixth, research shows that in the Lambda lifestyle of lysis, the protein activity along the bacterial cell DNA wormhole operates like a microscopic Einstein-Rosen bridge.”}}Literary AwardsExpanding the research on the Isis Thesis, Balls of Fire: A Science of Life and Death (2015) won 1st Place in “Body, Mind, Spirit” for Reader Views Literary Awards (2015-2016).[58] The study was also a Finalist in the 18th annual Foreword Reviews’ INDIEFAB Book of the Year Awards in the Nonfiction Adult category of “Body, Mind, Spirit.”[59] Paige Lovitt[60] reviewed the study for Reader Views in October, 2015: {{block indent |1=I found “Balls of Fire” by Judy K. King to be fascinating yet incredibly complex. The author obviously invested a great deal of time and energy into researching this phenomenon. King states that baseball was a game created by the pharaonic priesthood. The intent of this game was to demonstrate this scientific knowledge. Using the game of baseball as a method of explaining this knowledge also helps make it easier for the reader to visualize and understand. This book could be used as a textbook for a graduate level course. While reading, I found myself frequently seeking more information via the internet; not because “Balls of Fire” is lacking in anything, rather the newly gained knowledge stimulated my desire to learn more.}}CriticismThe quantum biology or microbiology in the Isis Thesis seem like science fiction due to its connections to black hole theory, cosmology, and quantum phenomena. Generally, the Isis Thesis has been ignored due to the complexity of its transdisciplinary knowledge (biology, microbiology, physics, cosmology, space physics, biochemistry). This is because, from a narrow single-disciplinary focus, the thesis seems incomprehensible due to its complex parts. Also, the thesis deals with an unappealing topic—virus and bacteria determining human behavior, as well as modeling the behavior of religious deities, and this conflicts with prevailing historical ideas of medicine and God. Further, the general Egyptological consensus on the funerary texts is that they are a compilation of magical spells,[61] which the Isis Thesis disputes. Also, theories that decode a hidden meaning are often dismissed, as Egyptologist Ogden Goelet, Jr.[62] explains: {{block indent |1=There is a vast corpus of non-Egyptological literature which claims that there is a hidden meaning to the BD [Book of the Dead] and other Egyptian religious texts. On the whole, Egyptologists have been quick to dismiss these theories, which are far too complex and numerous even to list here. . . Much of the BD is frankly incomprehensible, even for experts. No amount of exegesis can explain many passages. Images and allusions follow one another with bewildering force and frequency, lacking thematic and logical connection. The same can be said for much of the rest of Egyptian mortuary literature.}}Another issue is the quest for immortality in ancient Egyptian literature is difficult to take seriously, yet it challenges one to rethink the concept, according to Egyptologist Rune Nyord,[63] who believes the afterlife and quest for immortality are anachronistic ideas: {{block indent |1=I hope it has also become clear that the Egyptological notion of the quest for eternal life may in fact have functioned as an obstacle preventing us from taking Egyptian mortuary religion (and the many social practices connected with it) seriously, since we tend to regard beliefs in a transcendent afterlife as dislodged from social and cultural contexts.}}A similar challenge for the Isis Thesis is its comparison of the dying/rising viral lifestyles of phage Lambda with Egyptian and other religious dying/rising deities who obtain immortality. The Isis Thesis compares all these personal deities to phage Lambda’s viral activities at the level of genes and proteins (DNA), for the virus is dormant or dead (lysogeny) in the living human, and then it rises from the dead (lysis) due to E. coli’s SOS response in order to complete its lytic life cycle[64] [65] This suggests that religious human behavior is another microbial metabolic message indicating postmortem potential for survival of DNA through horizontal gene transfer and viral cloning or the lytic lifestyle of phage Lambda.[66] Ancient Egyptian texts describe the SOS response in E. coli that changes gene expression in response to DNA repair mechanisms.1 Still, the possibility of postmortem evolution is difficult to understand and often obscured due to conflicting cultural ideas concerning immortality, the afterlife,[67] the occult, magical phenomena and supernatural powers. Again, the Egyptological consensus is that the Egyptian texts are incomprehensible magical spells. On the other hand, the Isis Thesis claims that these magical spells suggest the ‘magic’ of quantum mechanics that is acausal, counterintuitive, and confusing, due to entanglement (phenomenon is which spatially distant particles have correlated properties), lawful time reverse, John Wheeler’s observer-participancy principle,[68] and other so-called supernatural qualities in the texts. On this fragile ground rests the Isis Thesis with its prediction of postmortem evolution of human DNA via HGT and transformation. When The Isis Thesis was published in 2004, the wild hypothesis that gut microbes, such as E. coli and its bacterial virus Lambda, could influence the human brain and behavior was generally ignored by scientific and Egyptological researchers. Yet, initial scientific studies since 2010 are showing that gut microbes do influence the brain and behavior. Links between the human brain, central nervous system, and gut microbiota are a major research focus for the future, according to an editorial in the Journal Nature (Feb 7, 2019).[69] Although many researchers believe symbiotic gut microbes have evolved to manipulate host behavior for their benefit, others argue that understanding why the gut microbiota influence behavior should focus on microbial ecology and local effects within the host.[70] Researchers argue that a rapidly-occurring process such as HGT might allow the holobiont (an assemblage of different species such as the human being) to survive under changing environmental conditions.[71] The Isis Thesis supports all of these perspectives. For a short review of The Isis Thesis (2004), see Natural Gift’s videotaped book review published on April 8, 2012.[72] For a longer review, see the author’s videotaped presentation on Evolution on September 29, 2015.[73] References1. ^{{cite book |last1=King |first1=Judy Kay |title=The Isis Thesis: a Study decoding 870 Ancient Egyptian Signs |date=2004 |publisher=Envision Editions Ltd. |location=Gaylord, MI USA |isbn=0976281406}} 2. ^{{cite book |last1=King |first1=Judy Kay |title=The Isis Thesis: a Study decoding 870 Ancient Egyptian Signs |date=2004 |publisher=Envision Editions Ltd. |location=Gaylord, MI USA |isbn=0976281406 |pages=410}} 3. ^{{cite news |last1=McWhirter |first1=Sheri |title=“Author links bacteria and Egyptian symbols: She’ll speak on subject at Cambridge.” |url=https://www.record-eagle.com/archives/author-links-bacteria-and-egyptian-symbols/article_20f2f53d-7f00-5e28-b946-5ede3f219bfe.html |accessdate=August 6, 2006 |agency=Traverse City Record Eagle Newspaper, Northern Michigan}} 4. ^{{cite web |title=Third International Conference on New Directions in the Humanities, University of Cambridge, United Kingdom, August 2-5, 2005 |url=http://h05.cgpublisher.com/proposals/809/index_html |publisher=Common Ground Research Networks}} 5. ^{{cite web |title=Humanities Conference 2005 Program for Third International Conference on New Directions in the Humanities, University of Cambridge, New Hall, UK, August 2-5, 2005 |url=http://h05.cgpublisher.com/H05_Program22_7.pdf ||ref=Presentation by Judy Kay King on Wednesday August 3, 2005, Room 9. See page 17}} 6. ^{{cite journal |last1=King |first1=Judy Kay |title="Biosemiotics in Ancient Egyptian Texts: The Key to Long-Lost Signs Found in Myth, Religion, Psychology, Art and Literature." |journal=The International Journal of the Humanities: Annual Review |date=2006 |volume=3 |issue=7 |page=189-204 |doi=10.18848/1447-9508/CGP/v03i07/41722}} 7. ^{{cite web |last1=King |first1=Judy Kay |title=Videotaped presentation of Judy Kay King at Second International Congress for Young Egyptologists, Lisbon, Museu da Farmácia Auditorium, October 23-26, 2006 |url=https://www.youtube.com/watch?v=L2cdX9MY-_g |website=www.youtube.com}} 8. ^{{cite web |title=Presentations at Museu da Farmácia Auditorium, October 23-26, 2006. |url=https://docplayer.com.br/12122286-Second-international-congress-for-young-egyptologists.html}} 9. ^{{cite web |last1=King |first1=Judy Kay |title=“Biosemiotics in Ancient Egyptian Texts: The Key Unlocking the Universal Secret of Sexuality and the Birth of the Limitless.” |url=https://edoc.site/birth-of-the-limitless-ancient-egypt-pdf-free.html |publisher=Published in ACTAS 2009 Proceedings for Second International Congress of Young Egyptologists, Lisboa 2006, DVD, pp. 281-298}} 10. ^{{cite book |last1=King |first1=Judy Kay |title=“Self-portrait in the Pharaoh’s Mirror: a Reflection of Ancient Egyptian Knowledge in Teilhard de Chardin’s Evolutionary Biophysics.” |date=October 4-7, 2007 |publisher=LEGAS and Semiotic Society of America |location=New York, Ontario |isbn=9781897493113 |pages=101-115 |edition=Semiotics 2006/2007, eds. Terry J. Prewitt and Wendy Morgan |ref=Presented at the 32nd Annual Meeting of the Semiotic Society of America, New Orleans, USA}} 11. ^{{cite book |last1=King |first1=Judy Kay |title=“The Order of the Harmonious Whole: Peirce’s Guess, Peregrinus’ Magnet, and Pharaoh’s Path.” |date=October 17, 2008 |publisher=LEGAS and Semiotic Society of America |location=New York, Ontario |isbn=9781897493144 |pages=179-190 |edition=Semiotics 2008, eds. John Deely and Leonard G. Sebrocchi |ref=Presented at the 33rd Annual Meeting of the Semiotic Society of America, Houston, USA}} 12. ^{{cite book |last1=King |first1=Judy Kay |title=Evolution Backward in Time: Crystals, Polyhedra and Observer-Participancy in the Cosmological Models of Peirce, Ancient Egypt and Early China.“ |date=October 17, 2009 |publisher=LEGAS and Semiotic Society of America |location=New York, Ontario |isbn=9781897493199 |pages=58-76 |edition=Semiotics 2009 The Semiotics of Time, eds. Karen Haworth, Jason Hogue, Leonard G. Sbrocchi |ref=Presented October 17, 2009, at the 34th Annual Meeting of SSA, Cincinnati, USA.}} 13. ^{{cite book |last1=King |first1=Judy Kay |title=“Ticket to Ride the Ancient Celestial Railroad: Natural Law, Worldview Knowledge, 'Evolutionary Love' and Ockham's Razor.“ |date=October 29, 2011 |publisher=LEGAS and Semiotic Society of America |location=New York, Ontario |isbn=9781897493366 |pages=137-155 |edition=The Semiotics of ??? Proceedings of the 36th Annual Meeting of SSA, 27-30 October 2011. eds. K. Haworth, J. Hogue, L. G. Sbrocchi |ref=Presented October 29, 2011, at the 36th Annual Meeting of SSA, Pittsburgh, USA}} 14. ^{{cite book |last1=King |first1=Judy Kay |title=The Road from Orion: a Surreal Story supporting the Isis Thesis |date=2004 |publisher=Envision Editions Ltd. |location=Gaylord, MI, USA |isbn=0976281414 |pages=190}} 15. ^{{cite book |last1=King |first1=Judy Kay |title=Balls of Fire: a Science of Life and Death |date=2015 |publisher=Envision Editions Ltd. |location=Gaylord, MI USA |isbn=9780976281429 |pages=302}} 16. ^{{cite journal |last1=King |first1=Judy Kay |title="Man the MisInterpretant: Will He Discover the Universal Secret of Sexuality Encoded Within Him?" |journal=The International Journal of the Humanities: Annual Review |date=2007 |volume=4 |issue=9 |pages=1-16 |doi=10.18848/1447-9508/CGP/v04i09/43436}} 17. ^{{cite journal |last1=King |first1=Judy Kay |title="From History’s Dustbin: A Semiotics of Evolvability Discovered within Man and his Mountain of Transformation." |journal=The International Journal of the Humanities: Annual Review |date=2007 |volume=5 |issue=5 |pages=113-126 |doi=10.18848/1447-9508/CGP/v05i05/42103}} 18. ^{{cite journal |last1=King |first1=Judy Kay |title="Cosmic Semiophysics in Ancient Architectual Vision: The Mountain Temples at Deir el Bahari, the Dead Sea Temple Scroll, and the Hagia Sophia." |journal=The International Journal of the Humanities: Annual Review |date=2008 |volume=6 |issue=4 |pages=17-26 |doi=10.18848/1447-9508/CGP/v06i04/42413}} 19. ^{{cite journal |last1=King |first1=Judy Kay |title="Cosmological Patterns in Ancient Egypt and China: The Way to Unify the Universe through Knowledge, Mind, Energy, and the Beneficence of the Elements." |journal=The International Journal of the Humanities: Annual Review |date=2009 |volume=7 |issue=2 |pages=151-166 |doi=10.18848/1447-9508/CGP/v07i02/42637}} 20. ^{{cite journal |last1=King |first1=Judy Kay |title="Unraveling Mountainway Ceremonials: Is Navajo Eschatological Ritual Another Semiotic Pattern of Ancient Invisible Magic Veiling a Complex Information System?" |journal=The International Journal of the Humanities: Annual Review |date=2011 |volume=8 |issue=12 |pages=45-80 |doi=10.18848/1447-9508/CGP/v08i12/43078}} 21. ^{{cite journal |last1=King |first1=Judy Kay |title="Death or the Powers: The Future of the Human Experience." |journal=The International Journal of Humanities Education |date=2014 |volume=11 |issue=3 |pages=1-17 |doi=10.18848/2327-0063/CGP/v11i03/43802}} 22. ^{{cite journal |last1=King |first1=Judy Kay |title=A Trace of Emergence: Human Social Behavior as a Sign of Microbial Metabolism |journal=The International Journal of Interdisciplinary Cultural Studies (Common Ground Research Networks) |date=2019}} 23. ^Kuhn, Jens H., Yuri I. Wolf, Mart Krupovic, Yong-Zhen Zhang, Piet Maes, Valerian V. Dolja, and Eugene V. Koonin. 2019. “Classify viruses—the gain is worth the pain.” Nature February 21, 566(7744): 318-320. 24. ^Carabotti, Marilia, Annunziata Scirocco, Maria Maselli, and Carola Severia. 2015. “Gut-brain axis.” Annals of Gastroenterology 28(2): 203–209 25. ^Wang, Hong-Xing, and Yu-Ping Wang. 2016. “Gut Microbiota-Brain Axis.” Chinese Medical Journal 129(19): 2373–2380. doi: 10.4103/0366-6999.190667 26. ^Cryan, J., and T. Dinan. 2012. “Mind-altering microorganisms.” Nature Reviews Neuroscience 13(10): 701–12. doi: 10.1038/nrn3346 27. ^Dinan, Timothy, Roman Stilling, Catherine Stanton, John Cryan. 2015. “Collective unconscious: How gut microbes shape human behavior.” Journal of Psychiatric Research 63: 1–9. DOI: https://doi.org/10.1016/j.jpsychires.2015.02.021 28. ^Zhang, Linda, and Sean Davies. 2016. “Microbial metabolism of dietary components to bioactive metabolites.” Genome Medicine 8: 46. doi: 10.1186/s13073-016-0296-x 29. ^Jenkins, Trisha, C. Jason, D. Nguyen, Kate Polglaze, Paul Bertrand. 2016. “Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis.” Nutrients 8(1): 56. doi: 10.3390/nu8010056.PMCID: PMC4728667 30. ^O’Mahony, S., G. Clarke, Y. Borre, T. Dinan, J. Cryan. 2015. “Serotonin, tryptophan metabolism and the brain-gut-microbiome axis.” Behavioural Brain Research 277: 32–48 31. ^Mayer, Emeran, Rob Knight, Sarkis Mazmanian, John Cryan, and Kirsten Tillisch. 2014. “Gut Microbes and the Brain.” Journal of Neuroscience 34(46): 15490–15496. doi: 10.1523/JNEUROSCI.3299-14.2014 32. ^2019 Editorial. “Gut feeling: The once radical idea that gut microbes affect mental health is now a major research pursuit.” Nature February 7, 2019, 566(7742): 7 33. ^Ibid., page 7 34. ^Johnson, Katerina, V.-A. and Kevin R. Foster. 2018. “Why does the microbiome affect behaviour?” Nature Reviews Microbiology. October 2016. Vol 16, 647-655. www.nature.com/nrmicro 35. ^Can, Ismail, Gulnaz Javan, Alexander Pozhitkov, Peter Noble. 2014. “Distinctive thanatomicrobiome signatures found in the blood and internal organs of humans.” Journal of Microbiological Methods 106: 1–7. DOI: 10.1016/j.mimet.2014.07.026 36. ^Vass, A., S-A. Barshick, G. Sega, J. Caton, J. Skeen, J. Love, J. Synstelien. 2002. “Decomposition chemistry of human remains.” Journal of Forensic Sciences 47(3): 542–553 37. ^Pozhitkov, Alex, Rafik Neme, Tomislav Domazet-Lošo, Brian Leroux, Shivani Soni, Diethard Tautz, and Peter Noble. 2016. “Thanatotranscriptome: genes actively expressed after organismal death.” BioRxiv doi: https://doi.org/10.1101/058305; Pozhitkov, Alex, Rafik Neme, Tomislav Domazet-Lošo, Brian Leroux, Shivani Soni, Diethard Tautz, and Peter Noble. 2017. “Tracing the dynamics of gene transcripts after organismal death.” Open Biology 7(1): 160267. https://doi.org/10.1098/rsob.160267 38. ^Gonzalez-Herrera L., A. Valenzuela, J. Marchal, J. Lorente, E. Villanueva. 2013. “Studies on RNA and gene expression in human myocardial tissue, pericardial fluid and blood, and its postmortem stability.” Forensic Science International 232(1–3): 218–228. https://www.ncbi.nlm.nih.gov/pubmed/24053884 or https://www.sciencedirect.com/science/article/pii/S0379073813003782?via%3Dihub 39. ^Ptashne, Mark. 2004. A Genetic Switch 3rd Edition: Phage Lambda Revisited. NY: Cold Spring Harbor Lab. Press 40. ^Sorensen, S. J., M. Bailey, L. H. Hansen, N. Kroer, and S. Wuertz. 2005. Studying plasmid horizontal gene transfer in situ: a critical review. Nature Reviews Microbiology (September), 3:700-710 41. ^. Liu L., X. Chen, G. Skogerbø, P. Zhang, R. Chen, S. He, D. W. Huang. 2012. “Human microbiome: a hot spot of microbial horizontal gene transfer.” Genomics 100(5): 265–70. doi: 10.1016/j.ygeno.2012.07.012. 42. ^Reyes, Alejandro, Nicholas Semenkovich, Katrine Whiteson, Forest Rohwer, Jeffrey Gordon. 2012. “Going Viral.” Nature Reviews Microbiology 10(9): 607–617. doi: 10.1038/nrmicro2853 43. ^Can, Ismail, Gulnaz Javan, Alexander Pozhitkov, Peter Noble. 2014. “Distinctive thanatomicrobiome signatures found in the blood and internal organs of humans.” Journal of Microbiological Methods 106: 1–7. DOI: 10.1016/j.mimet.2014.07.026 44. ^Vass, A., S-A. Barshick, G. Sega, J. Caton, J. Skeen, J. Love, J. Synstelien. 2002. “Decomposition chemistry of human remains.” Journal of Forensic Sciences 47(3): 542–553. 45. ^Farr, Spencer, and Tokio Kogoma. 1991. “Oxidative Stress Responses in Escherichia coli and Salmonella typhimurium.” Microbiological Reviews 55(4): 561–85 46. ^Carabotti, Marilia, Annunziata Scirocco, Maria Maselli, and Carola Severia. 2015. “Gut-brain axis.” Annals of Gastroenterology 28(2): 203–209 47. ^Wang, Hong-Xing, and Yu-Ping Wang. 2016. “Gut Microbiota-Brain Axis.” Chinese Medical Journal 129(19): 2373–2380. doi: 10.4103/0366-6999.190667 48. ^Cryan, J., and T. Dinan. 2012. “Mind-altering microorganisms.” Nature Reviews Neuroscience 13(10): 701–12. doi: 10.1038/nrn3346 49. ^Dinan, Timothy, Roman Stilling, Catherine Stanton, John Cryan. 2015. “Collective unconscious: How gut microbes shape human behavior.” Journal of Psychiatric Research 63: 1–9. DOI: https://doi.org/10.1016/j.jpsychires.2015.02.021 50. ^Zhang, Linda, and Sean Davies. 2016. “Microbial metabolism of dietary components to bioactive metabolites.” Genome Medicine 8: 46. doi: 10.1186/s13073-016-0296-x 51. ^Jenkins, Trisha, C. Jason, D. Nguyen, Kate Polglaze, Paul Bertrand. 2016. “Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis.” Nutrients 8(1): 56. doi: 10.3390/nu8010056.PMCID: PMC4728667 52. ^O’Mahony, S., G. Clarke, Y. Borre, T. Dinan, J. Cryan. 2015. “Serotonin, tryptophan metabolism and the brain-gut-microbiome axis.” Behavioural Brain Research 277: 32–48 53. ^Mayer, Emeran, Rob Knight, Sarkis Mazmanian, John Cryan, and Kirsten Tillisch. 2014. “Gut Microbes and the Brain.” Journal of Neuroscience 34(46): 15490–15496. doi: 10.1523/JNEUROSCI.3299-14.2014 54. ^2019 Editorial. “Gut feeling: The once radical idea that gut microbes affect mental health is now a major research pursuit.” Nature February 7, 2019, 566(7742): 7 55. ^King, Judy Kay. 2015. Balls of Fire: a Science of Life and Death (Gaylord, MI, USA: Envision Editions, Ltd.) 56. ^King, Judy Kay. 2019. “A Trace of Emergence: Human Social Behavior as a Sign of Microbial Metabolism.” Forthcoming in The International Journal of Interdisciplinary Cultural Studies. Common Ground Research Networks, Champaign, Illinois 57. ^King, J. K. 2009. “The Order of the Harmonious Whole: Peirce’s Guess, Peregrinus’ Magnet, and Pharaoh’s Path.” In Semiotics 2008. eds. John Deely and Leonard G. Sbrocchi. pp. 179-190; see pages 184-185 58. ^ On April 11, 2016, Balls of Fire, a Science of Life and Death won First Place under "Body, Mind, Spirit" for Reader Views Literary Awards (2015-2016). For the complete list. http://readerviews.com/2015-2016-literary-award-winners 59. ^Balls of Fire has been recognized as a Finalist in the 18th annual Foreword Reviews' INDIEFAB Book of the year Awards under the Adult Nonfiction category of "Body, Mind, Spirit." In the next three months, more than 130 librarians and booksellers will determine the winners, who will be celebrated at the American Library Association Annual Conference in Orlando in June 2016. https://www.forewordreviews.com/awards/books/balls-of-fire/ 60. ^Review of Balls of Fire by Paige Lovitt for Reader Views (October, 2015). http://readerviews.com/reviewkingballsoffire 61. ^Taylor, John H., ed. 2013. Journey through the Afterlife: Ancient Egyptian Book of the Dead. Harvard University Press 62. ^Goelet, Ogden, Jr. 1994. Introduction and Commentary to The Egyptian Book of the Dead. Trans. R. Faulkner. San Francisco: Chronicle Books. See page 153 of Commentary 63. ^Nyord, Rune. 2018. “Taking Ancient Egyptian Mortuary Religion Seriously: Why would we, and how could we?” Journal of Ancient Egyptian Interconnections Vol. 17 (March 2018): 73-87. http://jaei.library.arizona.edu 64. ^Ptashne, Mark. 2004. A Genetic Switch 3rd Edition. Phage Lambda Revisited. NY: Cold Spring Harbor Lab. Press 65. ^Reyes, Alejandro, Nicholas Semenkovich, Katrine Whiteson, Forest Rohwer, Jeffrey Gordon. 2012. “Going Viral.” Nature Reviews Microbiology 10(9): 607–617. doi: 10.1038/nrmicro2853 66. ^King, Judy Kay. 2015. Balls of Fire: a Science of Life and Death (Gaylord, MI, USA: Envision Editions, Ltd.). 67. ^Nyord, Rune. 2018. “Taking Ancient Egyptian Mortuary Religion Seriously: Why would we, and how could we?” Journal of Ancient Egyptian Interconnections Vol. 17 (March 2018): 73-87. http://jaei.library.arizona.edu 68. ^Wheeler, John Archibald. 1988. “World as System Self-synthesized by Quantum Networking.” IBM Journal of Research & Development 32: 4-15 69. ^2019 Editorial. “Gut feeling: The once radical idea that gut microbes affect mental health is now a major research pursuit.” Nature February 7, 2019, 566(7742): 7 70. ^Johnson, Katerina, V.-A. and Kevin R. Foster. 2018. “Why does the microbiome affect behaviour?” Nature Reviews Microbiology. October 2016. Vol 16, 647-655. www.nature.com/nrmicro 71. ^Zilber-Rosenberg, Ilana, and Eugene Rosenberg. 2008. “Role of microorganisms in the evolution of animals and plants.” FEMS Microbiology Reviews 32(5): 723–735. https://doi.org/10.1111/j.1574-6976.2008.00123.x 72. ^Videotaped review of The Isis Thesis (2004) by Natural Gift published April 8, 2012. “I really love this book. It is a brilliant, excellent read.” https://www.youtube.com/watch?v=pdlOGLwf06g 73. ^Videotaped presentation on evolution with Judy Kay King on September 29, 2015 at the University Center Gaylord, Michigan. Balls of Fire: a Science of Life and Death. https://www.youtube.com/watch?v=D4DDk4B3wWI |
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