| 词条 | Dsup |
| 释义 |
Tardigrades can withstand 1,000 times more radiation than other animals,[5] median lethal doses of 5,000 Gy (of gamma rays) and 6,200 Gy (of heavy ions) in hydrated animals (5 to 10 Gy could be fatal to a human).[7] The only explanation found in earlier experiments for this ability was that their lowered water state provides fewer reactants for ionizing radiation.[6] However, subsequent research found that tardigrades, when hydrated, still remain highly resistant to shortwave UV radiation in comparison to other animals, and that one factor for this is their ability to efficiently repair damage to their DNA resulting from that exposure.[7] The Dsup protein has been tested on other animal cells. Using a culture of human cells that express the Dsup protein, it was found that after X-ray exposure the cells had fewer DNA breaks than control cells.[2] References1. ^{{cite journal| pmc=5492148 | pmid=28617314 | doi=10.3390/life7020026 | volume=7 | issue=2 | pages=26 | title=DNA Protection Protein, a Novel Mechanism of Radiation Tolerance: Lessons from Tardigrades | year=2017 | journal=Life (Basel) | last1 = Hashimoto | first1 = T | last2 = Kunieda | first2 = T}} {{Protein-stub}}2. ^1 {{cite web|url=https://motherboard.vice.com/en_us/article/53dkz5/scientists-identify-gene-that-protects-tardigrades-from-radiation|title=Scientists Identify Gene That Protects Tardigrades From Radiation|last=Turk|first=Victoria|date=20 September 2016|work=Vice|accessdate=19 May 2018}} 3. ^{{cite news |last=Tauger |first=Nathan |last2= Gill |first2=Victoria |url=https://www.bbc.com/news/science-environment-37384466 |title=Survival secret of 'Earth's hardiest animal' revealed |work=BBC News |date=20 September 2016 |accessdate=2016-09-21 }} 4. ^1 {{cite journal |title=Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein |journal=Nature Communications |date=20 September 2015 |last=Hashimoto |first=Takuma | display-authors= etal |volume=7 |doi=10.1038/ncomms12808 |url=http://www.nature.com/ncomms/2016/160920/ncomms12808/full/ncomms12808.html |accessdate=2016-09-21 |page=12808 |pmid=27649274 |pmc=5034306}} 5. ^{{cite journal|last=Horikawa|first=Daiki D.| display-authors= etal|year=2006|title=Radiation tolerance in the tardigrade Milnesium tardigradum.|journal=International Journal of Radiation Biology|volume=82|issue=12|pages=843–848|issn=0955-3002|doi=10.1080/09553000600972956|pmid=17178624}} 6. ^1 {{cite journal|display-authors=8|last=Horikawa|first=Daiki D.|author2=Sakashita, Tetsuya|author3=Katagiri, Chihiro| author4= Watanabe, Masahiko| author5=Kikawada, Takahiro|author6=Nakahara, Yuichi|author7=Hamada, Nobuyuki|author8=Wada, Seiichi|author9=Funayama, Tomoo|author10=Higashi, Seigo| author11= Kobayashi, Yasuhiko| author12= Okuda, Takashi|author13=Kuwabara, Mikinori|title=Radiation tolerance in the tardigrade Milnesium tardigradum|journal=International Journal of Radiation Biology|date=1 January 2006|volume=82|issue=12|pages=843–848|doi=10.1080/09553000600972956|pmid=17178624}} 7. ^{{cite journal|last=Horikawa|first=Daiki D.|title=UV Radiation Tolerance of Tardigrades| url= https://astrobiology.nasa.gov/seminars/featured-seminar-channels/early-career-seminars/2012/04/24/uv-radiation-tolerance-of-tardigrades/ |publisher= NASA.com |accessdate= 2013-01-15}} 2 : Animal proteins|DNA-binding proteins |
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