| 词条 | DTP-HepB vaccine |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | image = | drug_name = DTP-HepB | type = combo | component1 = DTP vaccine | class1 = Vaccine | component2 = Hepatitis B vaccine | class2 = Vaccine | pronounce = | tradename = Tritanrix-HepB | Drugs.com = {{drugs.com|uk|Tritanrix-HepB}} | MedlinePlus = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_AU_comment = | legal_BR = | legal_BR_comment = | legal_CA = | legal_UK = | legal_US = | legal_UN = | legal_NZ = | legal_status = | routes_of_administration = Intramuscular injection | CAS_number = | ATCvet = | ATC_prefix = J07 | ATC_suffix = CA05 | PubChem = | DrugBank = }}DTP-HepB vaccine is a combination vaccine whose generic name is diphtheria and tetanus toxoids and whole-cell pertussis and hepatitis B (recombinant) vaccine (adsorbed) or DTP-Hep B. It protects against the infectious diseases diphtheria, tetanus, pertussis, and hepatitis B.[1] A branded formulation, Tritanrix-HepB manufactured by GlaxoSmithKline, was granted marketing approval in the EU in 1996. Marketing approval lapsed in 2014.[2] A review conducted in 2012 concluded that there was insufficient evidence to determine differences in safety and efficacy between DTP-HepB vaccine and Hib vaccine administered separately and pentavalent DTP-HepB-Hib vaccine.[3] References1. ^{{cite book |last1=Organization |first1=World Health |last2=Biologicals |first2=World Health Organization Department of Immunization, Vaccines and |title=Immunization in Practice: A Practical Guide for Health Staff |date=2004 |publisher=World Health Organization |isbn=9789241546515 |page=18 |url=https://books.google.com/books?id=cBBIreR5YR4C&pg=PT61&dq=DTP-HepB+vaccine&hl=en&sa=X&ved=0ahUKEwigvYeL9aDcAhVis1kKHTz1BuMQ6AEIJzAA#v=onepage&q=DTP-HepB%20vaccine&f=false |accessdate=15 July 2018 |language=en}} {{portal|Pharmacy and pharmacology}}{{Vaccines}}{{vaccine-stub}}2. ^{{cite web|url=http://www.ema.europa.eu/ema/pages/medicines/human/medicines/000093/human_med_001108.jsp|publisher=European Medicines Agency|title=Tritanrix HepB|access-date=14 July 2018}} 3. ^{{cite journal|last1=Bar-On|first1=Edna S|last2=Goldberg|first2=Elad|last3=Hellmann|first3=Sarah|last4=Leibovici|first4=Leonard|title=Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for primary prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B (HIB)|journal=Cochrane Database of Systematic Reviews|year=2012|issn=14651858|doi=10.1002/14651858.CD005530.pub3}} 7 : Vaccines|Combination drugs|Combination vaccines|Diphtheria|Tetanus|Pertussis|Hepatitis B |
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