The Ducati Superquadro engine is a 90° V-twin four-stroke motorcycle engine made by Ducati since 2011. It has Ducati's signature desmodromic valve system, with four valves per cylinder and gear/chain driven double overhead camshafts. It has been made in four displacements ranging from {{cvt|898|to|1285|cc}}, with power as high as {{cvt|145|kW}} in the largest version.

The Superquadro engine was first used in the {{cvt|1198|cc}} 1199 Panigale of 2011, with a bore and stroke of {{cvt|112|×|60.8|mm}}. This was followed in 2013 by a smaller {{cvt|898|cc}}, {{cvt|100|×|57.2|mm}} version, used in the 899 Panigale. The successor models, the 1299 Panigale of 2015 and the 959 Panigale of 2016, had the same {{cvt|60.8|mm}} stroke, and bores of either {{cvt|100|or|116|mm}}, giving displacements of {{cvt|1285|cc}}, and the {{cvt|955|cc}}.

Unlike the belt-driven overhead cams of earlier Ducati engines the Superquadro's uses gears and a chain. As with most Ducatis, the engine is a stressed member, making the bike smaller and lighter than a conventionally framed motorcycle.^[1] The engines are of aluminum with Cermetal bore plating, a hardening process developed by the Italian company Tecnol which is similar to Nikasil.^[2] A 1299 version of the engine has been made for the 2017 Ducati 1299 Superleggera model.^[3]

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