词条 | Eberconazole |
释义 |
| drug_name = | INN = | type = | IUPAC_name = 1-(1,3-Dichloro-6,11-dihydro-5H-dibenzo[1,2-a:1',4'-e][7]annulen-11-yl)imidazole | image = Eberconazole.svg | alt = | caption = | pronounce = | tradename = Ebernet | Drugs.com = | MedlinePlus = | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_US = | pregnancy_category= | routes_of_administration = | legal_AU = | legal_AU_comment = | legal_CA = | legal_DE = | legal_NZ = | legal_UK = | legal_US = Not FDA approved | legal_US_comment = | legal_UN = | legal_status = | bioavailability = | protein_bound = | metabolism = | metabolites = | onset = | elimination_half-life = | duration_of_action = | excretion = | CAS_number = 128326-82-9 | class = | ATCvet = | ATC_prefix = | ATC_suffix = | PubChem = 72051 | ChemSpiderID = 65038 | DrugBank = | C=18|H=14|Cl=2|N=2 | StdInChI=1S/C18H14Cl2N2/c19-14-9-13-6-5-12-3-1-2-4-15(12)18(17(13)16(20)10-14)22-8-7-21-11-22/h1-4,7-11,18H,5-6H2 | StdInChIKey=MPTJIDOGFUQSQH-UHFFFAOYSA-N | smiles = C1CC2=CC(=CC(=C2C(C3=CC=CC=C31)N4C=CN=C4)Cl)Cl }}Eberconazole is an antifungal drug. As a 1% topical cream, it is an effective treatment for dermatophytosis, candidiasis, and pityriasis.[1][2][3] It was approved for use in Spain in 2015 and is sold under the trade name Ebernet.[4] It is also approved for use in Panama, Guatemala, Costa Rica, Honduras, and the Dominican Republic.[1] References1. ^1 {{cite web | url = http://www.nbpharma.com/ebernet | publisher = NewBridge Pharmaceuticals | title = Ebernet}} {{dermatologic-drug-stub}}2. ^{{Cite journal | pmid = 11486455| year = 2001| author1 = Del Palacio| first1 = A| title = A double-blind randomized comparative trial: Eberconazole 1% cream versus clotrimazole 1% cream twice daily in Candida and dermatophyte skin infections| journal = Mycoses| volume = 44| issue = 5| pages = 173–80| last2 = Ortiz| first2 = F. J.| last3 = Pérez| first3 = A| last4 = Pazos| first4 = C| last5 = Garau| first5 = M| last6 = Font| first6 = E}} 3. ^{{Cite journal | pmid = 16700802| year = 2006| author1 = Repiso Montero| first1 = T| title = Eberconazole 1% cream is an effective and safe alternative for dermatophytosis treatment: Multicenter, randomized, double-blind, comparative trial with miconazole 2% cream| journal = International Journal of Dermatology| volume = 45| issue = 5| pages = 600–4| last2 = López| first2 = S| last3 = Rodríguez| first3 = C| last4 = Del Rio| first4 = R| last5 = Badell| first5 = A| last6 = Gratacós| first6 = M. R.| doi = 10.1111/j.1365-4632.2006.02841.x}} 4. ^{{cite web | url = https://www.drugs.com/international/eberconazole.html | title = Eberconazole | publisher = Drugs.com}} 2 : Imidazole antifungals|Lanosterol 14α-demethylase inhibitors |
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