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词条 Eberconazole
释义

  1. References

{{Infobox drug
| drug_name =
| INN =
| type =
| IUPAC_name = 1-(1,3-Dichloro-6,11-dihydro-5H-dibenzo[1,2-a:1',4'-e][7]annulen-11-yl)imidazole
| image = Eberconazole.svg
| alt =
| caption =
| pronounce =
| tradename = Ebernet
| Drugs.com =
| MedlinePlus =
| pregnancy_AU =
| pregnancy_AU_comment =
| pregnancy_US =
| pregnancy_category=
| routes_of_administration =
| legal_AU =
| legal_AU_comment =
| legal_CA =
| legal_DE =
| legal_NZ =
| legal_UK =
| legal_US = Not FDA approved
| legal_US_comment =
| legal_UN =
| legal_status =
| bioavailability =
| protein_bound =
| metabolism =
| metabolites =
| onset =
| elimination_half-life =
| duration_of_action =
| excretion =
| CAS_number = 128326-82-9
| class =
| ATCvet =
| ATC_prefix =
| ATC_suffix =
| PubChem = 72051
| ChemSpiderID = 65038
| DrugBank =
| C=18|H=14|Cl=2|N=2
| StdInChI=1S/C18H14Cl2N2/c19-14-9-13-6-5-12-3-1-2-4-15(12)18(17(13)16(20)10-14)22-8-7-21-11-22/h1-4,7-11,18H,5-6H2
| StdInChIKey=MPTJIDOGFUQSQH-UHFFFAOYSA-N
| smiles = C1CC2=CC(=CC(=C2C(C3=CC=CC=C31)N4C=CN=C4)Cl)Cl
}}Eberconazole is an antifungal drug. As a 1% topical cream, it is an effective treatment for dermatophytosis, candidiasis, and pityriasis.[1][2][3]

It was approved for use in Spain in 2015 and is sold under the trade name Ebernet.[4] It is also approved for use in Panama, Guatemala, Costa Rica, Honduras, and the Dominican Republic.[1]

References

1. ^{{cite web | url = http://www.nbpharma.com/ebernet | publisher = NewBridge Pharmaceuticals | title = Ebernet}}
2. ^{{Cite journal | pmid = 11486455| year = 2001| author1 = Del Palacio| first1 = A| title = A double-blind randomized comparative trial: Eberconazole 1% cream versus clotrimazole 1% cream twice daily in Candida and dermatophyte skin infections| journal = Mycoses| volume = 44| issue = 5| pages = 173–80| last2 = Ortiz| first2 = F. J.| last3 = Pérez| first3 = A| last4 = Pazos| first4 = C| last5 = Garau| first5 = M| last6 = Font| first6 = E}}
3. ^{{Cite journal | pmid = 16700802| year = 2006| author1 = Repiso Montero| first1 = T| title = Eberconazole 1% cream is an effective and safe alternative for dermatophytosis treatment: Multicenter, randomized, double-blind, comparative trial with miconazole 2% cream| journal = International Journal of Dermatology| volume = 45| issue = 5| pages = 600–4| last2 = López| first2 = S| last3 = Rodríguez| first3 = C| last4 = Del Rio| first4 = R| last5 = Badell| first5 = A| last6 = Gratacós| first6 = M. R.| doi = 10.1111/j.1365-4632.2006.02841.x}}
4. ^{{cite web | url = https://www.drugs.com/international/eberconazole.html | title = Eberconazole | publisher = Drugs.com}}
{{dermatologic-drug-stub}}

2 : Imidazole antifungals|Lanosterol 14α-demethylase inhibitors

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