| 词条 | Elizabeth Rakoczy |
| 释义 |
Elizabeth P. Rakoczy (née Piroska E. Szepessy) is a Hungarian-born molecular ophthalmologist. She is a professor at the University of Western Australia. She started the molecular ophthalmology department at the Lions Eye Institute. In 2017, Rakoczy was awarded the Florey Medal for her human gene therapy trial to modify viruses for the treatment of wet age-related macular degeneration. CareerRakoczy was born is Miskolc, Hungary.{{Citation needed|date=June 2018}} She started the Department of Molecular Ophthalmology at the Lions Eye Institute[1] and Professor of Molecular Ophthalmology at the University of Western Australia.[2] She was the Research Director of the Lions Eye Institute and the Centre of Ophthalmology and Visual Sciences between 1999-2009. Rakoczy's research focuses on gene therapy and animal model development. Her laboratory developed and sold the ’Kimba’ and ‘Akimba’ mouse models for advanced retinal neovascularization. She pioneered secretion gene therapy or ‘biofactory’ for the treatment of wet age related macular degeneration.[3][4][5] In 2011 it was licensed to Avalanche Biotechnologies Inc., (now Adverum Biotechnologies)[6], which used the technology to raise ~$300 Million. Rakoczy has published more than 180 scientific papers[7] in academic journals[4] and several patents. Awards and honorsRakoczy was a Bede Morris fellow of the Australian Academy of Science in 1998 and the National Health and Medical Research Council of Australia ‘Ten of the Best’ award winner in 2005 and winner of the CSL Florey Medal in 2017 for her human gene therapy trial modifying viruses to treat wet age-related macular degeneration.[8][9] Personal lifeShe is married and has two children.[10][11] References1. ^{{Cite news|url=https://www.lei.org.au/research/|title=Research Centre - Lions Eye Institute|work=Lions Eye Institute|access-date=2018-05-31 }} {{Authority control}}{{DEFAULTSORT:Rakoczy, Elizabeth}}2. ^{{Cite web|url=https://www.socrates.uwa.edu.au/Staff/StaffProfile.aspx?Person=PiroskaRakoczy|title=Socrates: Research Management Application|website=www.socrates.uwa.edu.au|access-date=2018-05-31}} 3. ^{{Citation|last=Elizabeth Rakoczy|title=Explaining gene therapy for wet AMD|date=2015-03-18|url=https://www.youtube.com/watch?v=CUiSFAi2_EY|accessdate=2018-05-31}} 4. ^1 {{Cite journal|last=Rakoczy|first=Elizabeth P|last2=Lai|first2=Chooi-May|last3=Magno|first3=Aaron L|last4=Wikstrom|first4=Matthew E|last5=French|first5=Martyn A|last6=Pierce|first6=Cora M|last7=Schwartz|first7=Steven D|last8=Blumenkranz|first8=Mark S|last9=Chalberg|first9=Thomas W|date= May 2015|title=Gene therapy with recombinant adeno-associated vectors for neovascular age-related macular degeneration: 1 year follow-up of a phase 1 randomised clinical trial | journal=The Lancet| volume=386|issue=10011|pages=2395–2403|doi=10.1016/S0140-6736(15)00345-1 }} 5. ^{{Cite journal|last=Constable|first=Ian J.|last2=Pierce|first2=Cora M.|last3=Lai|first3=Chooi-May|last4=Magno|first4=Aaron L.|last5=Degli-Esposti|first5=Mariapia A.|last6=French|first6=Martyn A.|last7=McAllister|first7=Ian L.|last8=Butler|first8=Steve|last9=Barone|first9=Samuel B.|date=2016-11-10|title=Phase 2a Randomized Clinical Trial: Safety and Post Hoc Analysis of Subretinal rAAV.sFLT-1 for Wet Age-related Macular Degeneration |journal=EBioMedicine|volume=14|pages=168–175|doi=10.1016/j.ebiom.2016.11.016 | pmc = 5161436 | pmid = 27865764 }} 6. ^{{Cite web|url=http://adverum.com/|title=Home - Adverum Biotechnologies|website=Adverum Biotechnologies |access-date=2018-05-31}} 7. ^{{Cite web|url=https://www.researchgate.net/profile/Piroska_Rakoczy|title=Piroska Elizabeth Rakoczy {{!}} PhD {{!}} University of Western Australia, Perth {{!}} UWA {{!}} Lions Eye Institute|last=PhD|first=Piroska Elizabeth RakoczyUniversity of Western Australia {{!}} UWA · Lions Eye Institute 40 88 ·|website=ResearchGate| access-date=2018-05-31}} 8. ^{{Cite news|url=http://www.aips.net.au/news-events/the-florey-medal/|title=CSL Florey Medal - AIPS|work=AIPS|access-date=2018-05-31 }} 9. ^{{Cite web|url=http://www.abc.net.au/radionational/programs/breakfast/researcher-who-uses-viruses-for-good-wins-csl-florey-medal/9234352|title=Researcher who uses viruses for good wins CSL Florey Medal|date=2017-12-07|website=Radio National |access-date=2018-06-02}} 10. ^{{Cite web|url=http://blog.mailasail.com/fenix|title=Fenix II ARC - Liz/Steve Rakoczy|website=blog.mailasail.com|access-date=2018-05-31}} 11. ^{{Cite web|url=http://www.austinmacauley.com/austin-macauley-publishers|title=Austin Macauley Publishers {{!}}{{!}} Books, eBooks & audiobooks|website=www.austinmacauley.com| access-date=2018-05-31}} 7 : 20th-century Australian scientists|21st-century Australian scientists|University of Western Australia faculty|People from Miskolc|Hungarian emigrants to Australia|Year of birth missing (living people)|Living people |
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