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词条 EmrB-Lactobacillus RNA motif
释义

  1. References

{{Infobox rfam
| Name = emrB-Lactobacillus
| image = RF02971.svg
| width =
| caption = Consensus secondary structure and sequence conservation of emrB-Lactobacillus RNA
| Symbol = emrB-Lactobacillus
| AltSymbols =
| Rfam = RF02971
| miRBase =
| miRBase_family =
| RNA_type = Gene; sRNA
| Tax_domain =
| GO =
| SO = {{SO|0001263}}
| CAS_number =
| EntrezGene =
| HGNCid =
| OMIM =
| RefSeq =
| Chromosome =
| Arm =
| Band =
| LocusSupplementaryData =
}}{{DISPLAYTITLE:emrB-Lactobacillus RNA motif}}

The emrB-Lactobacillus RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1]

emrB-Lactobacillus motifs are found in bacteria of the genus Lactobacillus.

emrB-Lactobacillus RNAs are generally located in the 5' untranslated regions of genes that encode EmrB, a kind of transporter. This fact suggests that the RNAs function as cis-regulatory elements. However, two factors call this conclusion into question. First, emrB-Lactobacillus RNAs are also located nearby to their upstream genes. Regulation of an upstream gene is unusual in bacteria. Second, some emrB-Lactobacillus RNAs are located nearby to transposase genes. The presence of these genes could suggest that emrB-Lactobacillus RNAs have a function related to transposons, although it is also consistent with the view that the apparent transposons have merely replicated nearby to the emrB-Lactobacillus RNAs by coincidence, and that there is no functional relationship between the two entities.

Thus, it is unknown whether emrB-Lactobacillus RNAs function as cis-regulatory RNAs or as small RNAs.

References

1. ^{{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811-10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 |url=}}

1 : Non-coding RNA

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