词条 | EmrB-Lactobacillus RNA motif |
释义 |
| Name = emrB-Lactobacillus | image = RF02971.svg | width = | caption = Consensus secondary structure and sequence conservation of emrB-Lactobacillus RNA | Symbol = emrB-Lactobacillus | AltSymbols = | Rfam = RF02971 | miRBase = | miRBase_family = | RNA_type = Gene; sRNA | Tax_domain = | GO = | SO = {{SO|0001263}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }}{{DISPLAYTITLE:emrB-Lactobacillus RNA motif}} The emrB-Lactobacillus RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] emrB-Lactobacillus motifs are found in bacteria of the genus Lactobacillus. emrB-Lactobacillus RNAs are generally located in the 5' untranslated regions of genes that encode EmrB, a kind of transporter. This fact suggests that the RNAs function as cis-regulatory elements. However, two factors call this conclusion into question. First, emrB-Lactobacillus RNAs are also located nearby to their upstream genes. Regulation of an upstream gene is unusual in bacteria. Second, some emrB-Lactobacillus RNAs are located nearby to transposase genes. The presence of these genes could suggest that emrB-Lactobacillus RNAs have a function related to transposons, although it is also consistent with the view that the apparent transposons have merely replicated nearby to the emrB-Lactobacillus RNAs by coincidence, and that there is no functional relationship between the two entities. Thus, it is unknown whether emrB-Lactobacillus RNAs function as cis-regulatory RNAs or as small RNAs. References1. ^{{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811-10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 |url=}} 1 : Non-coding RNA |
随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。