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词条 End organ
释义

The term end organ or end-organ has two meanings in medicine:

  • A small organ at the terminal end of a nerve conduction pathway
    • Bulbous corpuscle (Ruffini corpuscle end-organ)
    • Tactile corpuscle (Meissner corpuscle end-organ)
    • Merkel nerve ending (Merkel corpuscle end-organ)
    • Neuromuscular junction (motor end-organ)
    • Lamellar corpuscle (Pacinian corpuscle end-organ)
  • The ultimately affected organ in a chain of events, such as a disease process (pathophysiology) or a drug's mechanism of action (sometimes called a target organ in this sense)
    • End organ damage, disease of such organs
    • Ambulatory blood pressure § Target organ damage
    • Sepsis § End-organ dysfunction
    • HFE hereditary haemochromatosis § End-organ damage
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