“1,5-anhydro-D-fructose dehydratase”的意思、由来-开放百科全书

词条

1,5-anhydro-D-fructose dehydratase

释义

References
See also

{{enzyme
| Name = 1,5-anhydro-D-fructose dehydratase
| EC_number = 4.2.1.111
| CAS_number =
| IUBMB_EC_number = 4/2/1/111
| GO_code =
| image =
| width =
| caption =
}}

In enzymology, a 1,5-anhydro-D-fructose dehydratase ({{EC number|4.2.1.111}}) is an enzyme that catalyzes the chemical reaction

1,5-anhydro-D-fructose 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H₂O

Hence, this enzyme has one substrate, 1,5-anhydro-D-fructose, and two products, 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose and H₂O.

It catalyzes two steps in the anhydrofructose pathway process.^[1]

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 1,5-anhydro-D-fructose hydro-lyase (ascopyrone-M-forming). Other names in common use include 1,5-anhydro-D-fructose 4-dehydratase, 1,5-anhydro-D-fructose hydrolyase, 1,5-anhydro-D-arabino-hex-2-ulose dehydratase, AFDH, AF dehydratase, and 1,5-anhydro-D-fructose hydro-lyase.

References

1. ^IUBMB - Anhydrofructose Pathway

{{cite journal |vauthors=Yu S, Refdahl C, Lundt I | year = 2004 | title = Enzymatic description of the anhydrofructose pathway of glycogen degradation; I. Identification and purification of anhydrofructose dehydratase, ascopyrone tautomerase and alpha-1,4-glucan lyase in the fungus Anthracobia melaloma | journal = Biochim. Biophys. Acta | volume = 1672 | pages = 120–9 | pmid = 15110094 | issue = 2 | doi = 10.1016/j.bbagen.2004.03.004 }}
{{cite journal |vauthors=Yu S, Fiskesund R | year = 2006 | title = The anhydrofructose pathway and its possible role in stress response and signaling | journal = Biochim. Biophys. Acta | volume = 1760 | pages = 1314–22 | pmid = 16822618 | issue = 9 | doi = 10.1016/j.bbagen.2006.05.007 }}
{{cite journal | author = Yu S | year = 2005 | title = Enzymatic description of the anhydrofructose pathway of glycogen degradation II. Gene identification and characterization of the reactions catalyzed by aldos-2-ulose dehydratase that converts 1,5-anhydro-D-fructose to microthecin with ascopyrone M as the intermediate | journal = Biochim. Biophys. Acta | volume = 1723 | pages = 63–73 | pmid = 15716041 | issue = 1–3 | doi = 10.1016/j.bbagen.2005.01.004 }}

References

See also