“1,5-anhydro-D-fructose reductase”的意思、由来-开放百科全书

词条

1,5-anhydro-D-fructose reductase

释义

Structural studies
References

{{enzyme
| Name = 1,5-anhydro-D-fructose reductase
| EC_number = 1.1.1.263
| CAS_number = 206138-19-4
| IUBMB_EC_number = 1/1/1/263
| GO_code = 0050571
| image =
| width =
| caption =
}}

In enzymology, a 1,5-anhydro-D-fructose reductase ({{EC number|1.1.1.263}}) is an enzyme that catalyzes the chemical reaction

1,5-anhydro-D-glucitol + NADP⁺ 1,5-anhydro-D-fructose + NADPH + H⁺

Thus, the two substrates of this enzyme are 1,5-anhydro-D-glucitol and NADP⁺, whereas its 3 products are 1,5-anhydro-D-fructose, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 1,5-anhydro-D-glucitol:NADP⁺ oxidoreductase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code {{PDB link|2GLX}}.

References

{{cite journal |author1 = Sakuma M |author2 =Kametani S |author3 =Akanuma H | location = Tokyo | title = Purification and some properties of a hepatic NADPH-dependent reductase that specifically acts on 1,5-anhydro-D-fructose | journal = J. Biochem. | volume = 123| issue = 1 | pages = 189–193 | pmid=9504428 | date=January 1998 | doi=10.1093/oxfordjournals.jbchem.a021909}}

3 : EC 1.1.1|NADPH-dependent enzymes|Enzymes of known structure

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