词条 | Estradiol hexahydrobenzoate |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = (3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl) cyclohexanecarboxylate | image = Estradiol hexahydrobenzoate.svg | width = 250px | tradename = Benzo-Ginoestril A.P., BenzoGynoestryl Retard, Ginestryl-15-Depot, Menodin, Tardoginestryl | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intramuscular injection | class = Estrogen; Estrogen ester | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 15140-27-9 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | PubChem = 85808 | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 77397 | UNII = DI3496530P | synonyms = 17β-Hexahydrobenzoylestradiol; Estradiol 17β-cyclohexanecarboxylate | C=25 | H=34 | N= | O=3 | SMILES = CC12CCC3C(CCc4cc(O)ccc34)C1CCC2OC(=O)C5CCCCC5 | StdInChI_Ref = | StdInChI = 1S/C25H34O3/c1-25-14-13-20-19-10-8-18(26)15-17(19)7-9-21(20)22(25)11-12-23(25)28-24(27)16-5-3-2-4-6-16/h8,10,15-16,20-23,26H,2-7,9,11-14H2,1H3 | StdInChIKey_Ref = | StdInChIKey = IVRCALGRJCHPRV-UHFFFAOYSA-N }}Estradiol hexahydrobenzoate ({{abbrlink|INN|International Nonproprietary Name}}), sold under the brand names Benzo-Ginoestril A.P., BenzoGynoestryl Retard, Ginestryl-15-Depot, Menodin, and Tardoginestryl and also known as estradiol 17β-cyclohexanecarboxylate, is an estrogen and an estrogen ester which has been used in Europe.[1][2][3] It is an estrogen ester, specifically, an ester of estradiol.[1][2] It is or was marketed in France in a 5 mg/mL solution for intramuscular injection.[3] See also
References1. ^1 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=RA1-PA129|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=898}} {{Estrogens and antiestrogens}}{{Estrogen receptor modulators}}{{Genito-urinary-drug-stub}}{{Steroid-stub}}2. ^1 {{cite book|author1=I.K. Morton|author2=Judith M. Hall|title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA114|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-4439-1|pages=114, 206}} 3. ^1 {{cite book|author=Muller|title=European Drug Index: European Drug Registrations, Fourth Edition|url=https://books.google.com/books?id=2HBPHmclMWIC&pg=PA150|date=19 June 1998|publisher=CRC Press|isbn=978-3-7692-2114-5|pages=150–}} 2 : Estradiol esters|Estranes |
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