| 词条 | Estrone cyanate |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = 17-Oxoestra-1(10),2,4-trien-3-yl cyanate | image = Estrone cyanate.svg | width = 250px | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = By mouth | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 23623-36-1 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 26377079 | UNII = | KEGG = | ChEBI = | ChEMBL = | synonyms = Estrocyanate; Estrone 3-O-cyanate; Estrone 3-cyanate | C=19 | H=21 | N=1 | O=2 | molecular_weight = 295.380 g/mol | smiles = C[C@]12CC[C@@H]3c4ccc(cc4CC[C@H]3[C@@H]1CCC2=O)OC#N | StdInChI_Ref = | StdInChI = 1S/C19H21NO2/c1-19-9-8-15-14-5-3-13(22-11-20)10-12(14)2-4-16(15)17(19)6-7-18(19)21/h3,5,10,15-17H,2,4,6-9H2,1H3/t15-,16-,17+,19+/m1/s1 | StdInChIKey_Ref = | StdInChIKey = OIOQBNDENVAFEU-VXNCWWDNSA-N }}Estrone cyanate, or estrone 3-O-cyanate, also known as estrocyanate, is an estrogen and an estrogen ester – specifically, the 3-O-cyanate ester of estrone – which was investigated for potential use in birth control pills but was found to be of relatively low potency and ultimately was never marketed.[1][2][3][4] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA900|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|page=900}} {{Estrogen receptor modulators}}{{Steroid-stub}}{{Genito-urinary-drug-stub}}2. ^{{cite book|title=Endokrinologie|volume=59|publisher=Johann Ambrosius Barth Verlag|url=https://books.google.com/books?id=NZi3AAAAIAAJ|year=1972|page=293}} 3. ^{{cite journal | vauthors = Göretzlehner G, Kühne D, Dässler CG | title = [Experimental studies with the new synthetic estrogen, estrocyanate] | language = German | journal = Dtsch Gesundheitsw | volume = 26 | issue = 34 | pages = 1614–7 | date = August 1971 | pmid = 5117100 | doi = | url = }} 4. ^{{cite journal | vauthors = Carol W, Klinger G, Hempel E, Böhm W, Chemnitius KH | title = [Experimental and clinical studies with new estrogen derivatives] | language = German | journal = Endokrinologie | volume = 59 | issue = 3 | pages = 282–94 | year = 1972 | pmid = 5071777 | doi = | url = }} 6 : Abandoned drugs|Cyanates|Esters|Estranes|Estrogen esters|Estrogens |
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