| 词条 | Ethambutol/isoniazid/pyrazinamide/rifampicin |
| 释义 |
| drug_name = | type = combo | component1 = Ethambutol | class1 = Anti-tuberculosis medication | component2 = Isoniazid | class2 = Anti-tuberculosis medication | component3 = Pyrazinamide | class3 = Anti-tuberculosis medication | component4 = Rifampicin | class4 = Anti-tuberculosis medication | pronounce = | tradename = Voractiv, Rimstar, others | Drugs.com = | MedlinePlus = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_AU_comment = | legal_CA = | legal_UK = | legal_US = | legal_UN = | legal_NZ = | legal_status = | routes_of_administration = | CAS_number = | ATCvet = | ATC_prefix = J04A | ATC_suffix = M06 | PubChem = | DrugBank = | ChemSpiderID = none }}Ethambutol/isoniazid/pyrazinamide/rifampicin, also known as ethambutol/isoniazid/pyrazinamide/rifampin, is a medication used for tuberculosis.[1] It is a fixed dose combination of ethambutol, isoniazid, pyrazinamide, and rifampicin.[1] It is used either alone or with other antituberculosis medication.[1] It is taken by mouth.[1] Side effects are those of the underlying medications.[1] Pyridoxine may be used to decrease the risk of numbness.[6] It is not recommended in people with liver problems or severe kidney problems.[2] Use may not be suitable in children.[1] It is unclear if use during pregnancy is safe.[2] It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[3] In the United Kingdom it costs the NHS 98.75 pounds for a typical month of medication as of 2015.[4] It is sold under the brand names Voractiv and Rimstar in the UK.[2] References1. ^1 2 3 4 5 {{cite book|title=WHO Model Formulary 2008|date=2009|publisher=World Health Organization|isbn=9789241547659|page=142|url=http://apps.who.int/medicinedocs/documents/s16879e/s16879e.pdf|accessdate=8 December 2016|deadurl=no|archiveurl=https://web.archive.org/web/20161213060118/http://apps.who.int/medicinedocs/documents/s16879e/s16879e.pdf|archivedate=13 December 2016|df=}} {{portal bar|Pharmacy and pharmacology|Medicine}}2. ^1 2 {{cite web|title=Rimstar Film-coated Tablet / Voractiv Film-coated Tablet - Summary of Product Characteristics (SPC) - (eMC)|url=https://www.medicines.org.uk/emc/medicine/27483|website=www.medicines.org.uk|accessdate=18 December 2016|date=February 2016|deadurl=no|archiveurl=https://web.archive.org/web/20161220193444/https://www.medicines.org.uk/emc/medicine/27483|archivedate=20 December 2016|df=}} 3. ^{{cite web|title=WHO Model List of Essential Medicines (19th List)|url=http://www.who.int/medicines/publications/essentialmedicines/EML_2015_FINAL_amended_NOV2015.pdf?ua=1|work=World Health Organization|accessdate=8 December 2016|date=April 2015|deadurl=no|archiveurl=https://web.archive.org/web/20161213052708/http://www.who.int/medicines/publications/essentialmedicines/EML_2015_FINAL_amended_NOV2015.pdf?ua=1|archivedate=13 December 2016|df=}} 4. ^1 {{cite book|title=British national formulary : BNF 69|date=2015|publisher=British Medical Association|isbn=9780857111562|page=403|edition=69}} 4 : Tuberculosis|Combination drugs|World Health Organization essential medicines|RTT |
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