- References
| Name = 17α-Hydroxyprogesterone aldolase
| EC_number = 4.1.2.30
| CAS_number = 62213-24-5
| IUBMB_EC_number = 4/1/2/30
| GO_code = 0047442
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In enzymology, a 17α-hydroxyprogesterone aldolase ({{EC number|4.1.2.30}}) is an enzyme that catalyzes the chemical reaction
17α-hydroxyprogesteroneandrost-4-en-3,17-dione + acetaldehyde
Hence, this enzyme has one substrate, 17α-hydroxyprogesterone, and two products, androst-4-en-3,17-dione and acetaldehyde.
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 17α-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming). Other names in common use include C-17/C-20-lyase, and 17α-hydroxyprogesterone acetaldehyde-lyase. This enzyme participates in androgen and estrogen metabolism.
References
- {{cite journal |vauthors=Nowotny E, Sananez RD, Nattero G, Yantorno C, Faillaci MG | date = 1974 | title = Bioconversion of steroids in vitro by testes from autoimmunized rabbits | journal = Hoppe-Seyler's Z. Physiol. Chem. | volume = 355 | pages = 716–20 | pmid = 4435747 | issue = 6 | doi = 10.1515/bchm2.1974.355.1.716 }}
2 : EC 4.1.2|Enzymes of unknown structure