词条 | Evx1 |
释义 |
Despite a regulatory role in both of these processes, the Evx1 KO mouse is viable and displays no overt phenotype after birth.[4][6] A divergent long non-coding RNA (Evx1as) is also expressed from the locus, which is temporally and spatially co-expressed with Evx1.[3][4][7] Evx1as does not have a function beyond that of Evx1 (in trans),[4] however it has been shown to regulate Evx1 at the locus (in cis).[7] References1. ^{{Cite journal|last=Nüsslein-Volhard|first=Christiane|last2=Wieschaus|first2=Eric|date=1980-10-30|title=Mutations affecting segment number and polarity in Drosophila|url=http://www.nature.com/nature/journal/v287/n5785/abs/287795a0.html|journal=Nature|language=en|volume=287|issue=5785|pages=795–801|doi=10.1038/287795a0|pmid=6776413}} 2. ^{{Cite journal|last=Manoukian|first=A. S.|last2=Krause|first2=H. M.|date=1992-09-01|title=Concentration-dependent activities of the even-skipped protein in Drosophila embryos.|url=http://genesdev.cshlp.org/content/6/9/1740|journal=Genes & Development|language=en|volume=6|issue=9|pages=1740–1751|doi=10.1101/gad.6.9.1740|issn=0890-9369|pmid=1355458}} 3. ^1 {{Cite journal|last=Dinger|first=Marcel E.|last2=Amaral|first2=Paulo P.|last3=Mercer|first3=Tim R.|last4=Pang|first4=Ken C.|last5=Bruce|first5=Stephen J.|last6=Gardiner|first6=Brooke B.|last7=Askarian-Amiri|first7=Marjan E.|last8=Ru|first8=Kelin|last9=Soldà|first9=Giulia|date=2008-09-01|title=Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation|url=http://genome.cshlp.org/content/18/9/1433|journal=Genome Research|language=en|volume=18|issue=9|pages=1433–1445|doi=10.1101/gr.078378.108|issn=1088-9051|pmc=2527704|pmid=18562676}} 4. ^1 2 3 4 {{Cite journal|last=Bell|first=Charles C.|last2=Amaral|first2=Paulo P.|last3=Kalsbeek|first3=Anton|last4=Magor|first4=Graham W.|last5=Gillinder|first5=Kevin R.|last6=Tangermann|first6=Pierre|last7=Lisio|first7=Lorena di|last8=Cheetham|first8=Seth W.|last9=Gruhl|first9=Franziska|date=2016-05-26|title=The Evx1/Evx1as gene locus regulates anterior-posterior patterning during gastrulation|url=http://www.nature.com/articles/srep26657|journal=Scientific Reports|language=en|volume=6|doi=10.1038/srep26657|issn=2045-2322|pages=26657|pmid=27226347|pmc=4880930}} 5. ^{{Cite journal|last=Kalisz|first=Mark|last2=Winzi|first2=Maria|last3=Bisgaard|first3=Hanne Cathrine|last4=Serup|first4=Palle|date=2012-02-01|title=EVEN-SKIPPED HOMEOBOX 1 controls human ES cell differentiation by directly repressing GOOSECOID expression|url=http://www.sciencedirect.com/science/article/pii/S0012160611013996|journal=Developmental Biology|volume=362|issue=1|pages=94–103|doi=10.1016/j.ydbio.2011.11.017|pmid=22178155}} 6. ^1 {{Cite journal|last=Moran-Rivard|first=Laura|last2=Kagawa|first2=Tetsushi|last3=Saueressig|first3=Harald|last4=Gross|first4=Michael K.|last5=Burrill|first5=John|last6=Goulding|first6=Martyn|date=2001-02-01|title=Evx1 Is a Postmitotic Determinant of V0 Interneuron Identity in the Spinal Cord|url=http://www.cell.com/article/S0896627301002136/abstract|journal=Neuron|language=English|volume=29|issue=2|pages=385–399|doi=10.1016/S0896-6273(01)00213-6|issn=0896-6273|pmid=11239430}} 7. ^1 {{Cite journal|last=Luo|first=Sai|last2=Lu|first2=J. Yuyang|last3=Liu|first3=Lichao|last4=Yin|first4=Yafei|last5=Chen|first5=Chunyan|last6=Han|first6=Xue|last7=Wu|first7=Bohou|last8=Xu|first8=Ronggang|last9=Liu|first9=Wei|date=2016-05-05|title=Divergent lncRNAs Regulate Gene Expression and Lineage Differentiation in Pluripotent Cells|url=http://www.cell.com/article/S193459091600062X/abstract|journal=Cell Stem Cell|language=English|volume=18|issue=5|pages=637–652|doi=10.1016/j.stem.2016.01.024|issn=1934-5909|pmid=26996597}} 1 : Genes |
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