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词条 Filicin
释义

  1. Related compounds

  2. References

{{Chembox
| ImageFile = Filicin.svg
| ImageSize = 200px
| IUPACName = 2-Butanoyl-4-[[3-butanoyl-5-[(5-butanoyl-2,6-dihydroxy-3,3-dimethyl-4-oxocyclohexa-1,5-dien-1-yl)methyl]-2,4,6-trihydroxyphenyl]methyl]-3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one
| OtherNames = Filixic acid BBB; Filixic acid
| Section1 = {{Chembox Identifiers
| CASNo = 4482-83-1
| PubChem = 197044
| EINECS = 224-766-2
| UNII = 3OQ8CMM2OZ
| ChEBI = 5060
| KEGG = C10693
| StdInChI=1S/C36H44O12/c1-8-11-20(37)23-27(41)16(14-18-29(43)24(21(38)12-9-2)33(47)35(4,5)31(18)45)26(40)17(28(23)42)15-19-30(44)25(22(39)13-10-3)34(48)36(6,7)32(19)46/h40-46H,8-15H2,1-7H3
| StdInChIKey = FRTCWDLFHSMTNW-UHFFFAOYSA-N
| SMILES = CCCC(=O)C1=C(C(=C(C(=C1O)CC2=C(C(C(=O)C(=C2O)C(=O)CCC)(C)C)O)O)CC3=C(C(C(=O)C(=C3O)C(=O)CCC)(C)C)O)O
| Section2 = {{Chembox Properties
| C=36|H=44|O=12
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
| Section3 = {{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}Filicin is a chemical compound that has been isolated from ferns of the genus Dryopteris. It has been isoloated from the male fern (Dryopteris filix-mas).[1] Filicin has been studied for its anthelmintic activity.[2]

Related compounds

A variety of chemically related compounds, sometimes referred to collectively as filicins, have also been isolated from ferns. Chemical analysis of filicins in fern extracts can assist in determining taxonomy.[3] Examples of filicins include:

Name(s) Chemical structure Molecular formula Molecular weight (g/mol) CAS number PubChem Notes
Filixic acid ABA C32H36O12 612.63 38226-84-515081408}} First isolated from Dryopteris dickinsii[4]
Filixic acid ABP C33H38O12 626.66 57765-54-573672225}} [5]
Filixic acid ABB C34H40O12 640.68 37318-24-4102574620}} Found in Dryopteris sieboldii[5]
Filixic acid PBP C34H40O12 640.68 51005-85-720055092}} Found in Dryopteris filix-mas[6]
Filixic acid PBB C35H42O12 654.71 49582-09-420055091}} [7]
Flavaspidic acid BB; Toxifren; Polystichocitrin; Glavaspidic acid C24H30O8 446.49 114-42-18237}} Isolated from Dryopteris abbreviata[8]

References

1. ^{{cite web | url = https://chem.nlm.nih.gov/chemidplus/rn/4482-83-1 | title = Filicin | work = TOXNET | publisher = U.S. National Library of Medicine}}
2. ^{{cite journal | pmid = 13953368| year = 1963| author1 = Heikinheimo| first1 = R| title = Effect of filicin administered as an anthelmintic on the coagulation factors of the blood| journal = Annales Medicinae Internae Fenniae| volume = 52| pages = 93–6}}
3. ^{{cite journal | title = Chemotaxonomy in Dryopteris and related fern genera | authors = Euw, J. v.; Lounasmaa, M.; Reichstein, T.; and Widén, C.J. | url = https://www.openstarts.units.it/handle/10077/14793 | journal = Studia Geobotanica | volume = 1 | date = 1980 | pages = 275–311}}
4. ^{{Cite journal | title = Pharmaceutical studies on Japanese ferns containing phloroglucinol derivatives. 9 Constituents of Dryopteris dickinsii | author = Hisada, Sueo; Shiraishi, Koichi; Inagaki, Isao | journal = Yakugaku Zasshi | date = 1972 | volume = 92 | issue = 9 | pages = 1124–1128}}
5. ^{{cite journal | title = Phloroglucinol derivatives of Dryopteris sieboldii | author = Hisada, Sueo; Inoue, O.; Inagak, Isao | journal = Phytochemistry | date = 1973 | volume = 12 | issue = 8 | pages = 2055}}
6. ^{{cite journal | title = Isolation and HPLC method development for filixic acid PBP from Dryopteris filix-mas | author = Katekhaye, S. D.; Shinde, P. B.; Laddha, K. S. | journal = International Journal of Phytopharmacy | date = 2011 | volume = 1 | issue = 1 | pages = 1–7}}
7. ^{{Cite journal | pmid = 1197418| year = 1975| author1 = Widén| first1 = C. J| title = Phloroglucinol derivatives of eleven Dryopteris species from Japan| journal = Planta Medica| volume = 28| issue = 2| pages = 144–64| last2 = Lounasmaa| first2 = M| last3 = Sarvela| first3 = J}}
8. ^{{Cite journal | doi = 10.1016/0031-9422(82)80168-4| title = A phloroglucinol derivative of Dryopteris abbreviata| journal = Phytochemistry| volume = 21| issue = 6| pages = 1453| year = 1982| last1 = Coşkun| first1 = Maksut| last2 = Sakushima| first2 = Akiyo| last3 = Nishibe| first3 = Sansei| last4 = Hisada| first4 = Sueo| last5 = Tanker| first5 = Nevin}}

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