词条 | Fluoroethyl-L-tyrosine (18F) |
释义 |
| Watchedfields = | verifiedrevid = | IUPAC_name = (2S)-2-Amino-3-[4-(2-fluoroethoxy)phenyl]propanoic acid | image = FET structure.png | width = 200 | drug_name = Fluoroethyl-L-tyrosine (18F) | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intravenous | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | IUPHAR_ligand = | CAS_number_Ref = | CAS_number = | CAS_supplemental = | ATC_prefix = V09 | ATC_suffix = IX10 | DrugBank_Ref = | DrugBank = | PubChem = 9834479 | ChemSpiderID = 8010200 | UNII_Ref = | UNII = 3Y68K91A3M | KEGG_Ref = | KEGG = | ChEBI_Ref = | ChEBI = | ChEMBL_Ref = | ChEMBL = | NIAID_ChemDB = | C=11 | H=14 | N=1 | O=3 | F=1 | molecular_weight = 227.23 g/mol | smiles = C1=CC(=CC=C1C[C@@H](C(=O)O)N)OCC[18F] | StdInChI = 1S/C11H14FNO3/c12-5-6-16-9-3-1-8(2-4-9)7-10(13)11(14)15/h1-4,10H,5-7,13H2,(H,14,15)/t10-/m0/s1/i12-1 | StdInChIKey = QZZYPHBVOQMBAT-LRAGLOQXSA-N | synonyms = 18F-FET; O-(2-(18F)fluoroethyl)-L-tyrosine, O-(2-Fluorethyl)-L-thyrosine, L-(18F)FET[1] }}Fluoroethyl-L-tyrosine (18F) or 18F-FET is a neuro-oncologic PET tracer.[2] References1. ^{{PubChem|54255856}} {{Diagnostic radiopharmaceuticals}}{{pharma-stub}}2. ^{{cite journal | url = http://neuro-oncology.oxfordjournals.org/content/early/2015/05/24/neuonc.nov088.abstract | doi = 10.1093/neuonc/nov088| title = The use of dynamic O-(2-18F-fluoroethyl)-L-tyrosine PET in the diagnosis of patients with progressive and recurrent glioma| journal = Neuro-Oncology| year = 2015| last1 = Galldiks| first1 = N.| last2 = Stoffels| first2 = G.| last3 = Filss| first3 = C.| last4 = Rapp| first4 = M.| last5 = Blau| first5 = T.| last6 = Tscherpel| first6 = C.| last7 = Ceccon| first7 = G.| last8 = Dunkl| first8 = V.| last9 = Weinzierl| first9 = M.| last10 = Stoffel| first10 = M.| last11 = Sabel| first11 = M.| last12 = Fink| first12 = G. R.| last13 = Shah| first13 = N. J.| last14 = Langen| first14 = K.-J.| pmc = 4588758}} 2 : PET radiotracers|Amino acid derivatives |
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