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词条 Fluoroethyl-L-tyrosine (18F)
释义

  1. References

{{DISPLAYTITLE:Fluoroethyl-L-tyrosine (18F)}}{{Drugbox
| Watchedfields =
| verifiedrevid =
| IUPAC_name = (2S)-2-Amino-3-[4-(2-fluoroethoxy)phenyl]propanoic acid
| image = FET structure.png
| width = 200
| drug_name = Fluoroethyl-L-tyrosine (18F)
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration = Intravenous
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| IUPHAR_ligand =
| CAS_number_Ref =
| CAS_number =
| CAS_supplemental =
| ATC_prefix = V09
| ATC_suffix = IX10
| DrugBank_Ref =
| DrugBank =
| PubChem = 9834479
| ChemSpiderID = 8010200
| UNII_Ref =
| UNII = 3Y68K91A3M
| KEGG_Ref =
| KEGG =
| ChEBI_Ref =
| ChEBI =
| ChEMBL_Ref =
| ChEMBL =
| NIAID_ChemDB =
| C=11 | H=14
| N=1 | O=3
| F=1
| molecular_weight = 227.23 g/mol
| smiles = C1=CC(=CC=C1C[C@@H](C(=O)O)N)OCC[18F]
| StdInChI = 1S/C11H14FNO3/c12-5-6-16-9-3-1-8(2-4-9)7-10(13)11(14)15/h1-4,10H,5-7,13H2,(H,14,15)/t10-/m0/s1/i12-1
| StdInChIKey = QZZYPHBVOQMBAT-LRAGLOQXSA-N
| synonyms = 18F-FET; O-(2-(18F)fluoroethyl)-L-tyrosine, O-(2-Fluorethyl)-L-thyrosine, L-(18F)FET[1]
}}Fluoroethyl-L-tyrosine (18F) or 18F-FET is a neuro-oncologic PET tracer.[2]

References

1. ^{{PubChem|54255856}}
2. ^{{cite journal | url = http://neuro-oncology.oxfordjournals.org/content/early/2015/05/24/neuonc.nov088.abstract | doi = 10.1093/neuonc/nov088| title = The use of dynamic O-(2-18F-fluoroethyl)-L-tyrosine PET in the diagnosis of patients with progressive and recurrent glioma| journal = Neuro-Oncology| year = 2015| last1 = Galldiks| first1 = N.| last2 = Stoffels| first2 = G.| last3 = Filss| first3 = C.| last4 = Rapp| first4 = M.| last5 = Blau| first5 = T.| last6 = Tscherpel| first6 = C.| last7 = Ceccon| first7 = G.| last8 = Dunkl| first8 = V.| last9 = Weinzierl| first9 = M.| last10 = Stoffel| first10 = M.| last11 = Sabel| first11 = M.| last12 = Fink| first12 = G. R.| last13 = Shah| first13 = N. J.| last14 = Langen| first14 = K.-J.| pmc = 4588758}}
{{Diagnostic radiopharmaceuticals}}{{pharma-stub}}

2 : PET radiotracers|Amino acid derivatives

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