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词条 Fourphit
释义

  1. See also

  2. References

{{Chembox
| ImageFile = Fourphit.png
| ImageSize = 200px
| ImageAlt =
| IUPACName =
| OtherNames =
| Section1 = {{Chembox Identifiers
| CASNo =
| PubChem = 128615
| ChemSpiderID = 113988
| SMILES = c1ccc(cc1)C2(CCCCC2)N3CCC(CC3)N=C=S
| InChI = 1/C18H24N2S/c21-15-19-17-9-13-20(14-10-17)18(11-5-2-6-12-18)16-7-3-1-4-8-16/h1,3-4,7-8,17H,2,5-6,9-14H2
| InChIKey = QAHYIAVTWZVTMY-UHFFFAOYAR
| StdInChI = 1S/C18H24N2S/c21-15-19-17-9-13-20(14-10-17)18(11-5-2-6-12-18)16-7-3-1-4-8-16/h1,3-4,7-8,17H,2,5-6,9-14H2
| StdInChIKey = QAHYIAVTWZVTMY-UHFFFAOYSA-N
| Section2 = {{Chembox Properties
| C=18 | H = 24 | N=2 | S=1
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
| Section3 = {{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}Fourphit (4-isothiocyanato-1-[1-phenylcyclohexyl]piperidine) is a covalent binding NMDA antagonist, dopaminergic and sigma receptor agonist.[1]

See also

  • Metaphit

References

1. ^{{cite journal | pmid = 9678644 | year = 1998 | author1 = Schweri | first1 = M. M. | title = Fourphit, an acylating phencyclidine derivative, attenuates cocaine-induced hyperactivity in rats | journal = Pharmacology Biochemistry and Behavior | volume = 60 | issue = 3 | pages = 615–23 | last2 = De Costa | first2 = B. R. | last3 = Rice | first3 = K. C. | doi=10.1016/s0091-3057(98)00040-9}}
{{Navboxes
| title = Pharmacodynamics
| titlestyle = background:#ccccff
| list1 ={{Ionotropic glutamate receptor modulators}}{{Monoamine reuptake inhibitors}}{{Sigma receptor modulators}}
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6 : Dopamine reuptake inhibitors|Dissociative drugs|NMDA receptor antagonists|Piperidines|Sigma agonists|Isothiocyanates

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