词条 | Fourphit |
释义 |
| ImageFile = Fourphit.png | ImageSize = 200px | ImageAlt = | IUPACName = | OtherNames = | Section1 = {{Chembox Identifiers | CASNo = | PubChem = 128615 | ChemSpiderID = 113988 | SMILES = c1ccc(cc1)C2(CCCCC2)N3CCC(CC3)N=C=S | InChI = 1/C18H24N2S/c21-15-19-17-9-13-20(14-10-17)18(11-5-2-6-12-18)16-7-3-1-4-8-16/h1,3-4,7-8,17H,2,5-6,9-14H2 | InChIKey = QAHYIAVTWZVTMY-UHFFFAOYAR | StdInChI = 1S/C18H24N2S/c21-15-19-17-9-13-20(14-10-17)18(11-5-2-6-12-18)16-7-3-1-4-8-16/h1,3-4,7-8,17H,2,5-6,9-14H2 | StdInChIKey = QAHYIAVTWZVTMY-UHFFFAOYSA-N | Section2 = {{Chembox Properties | C=18 | H = 24 | N=2 | S=1 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Fourphit (4-isothiocyanato-1-[1-phenylcyclohexyl]piperidine) is a covalent binding NMDA antagonist, dopaminergic and sigma receptor agonist.[1] See also
References1. ^{{cite journal | pmid = 9678644 | year = 1998 | author1 = Schweri | first1 = M. M. | title = Fourphit, an acylating phencyclidine derivative, attenuates cocaine-induced hyperactivity in rats | journal = Pharmacology Biochemistry and Behavior | volume = 60 | issue = 3 | pages = 615–23 | last2 = De Costa | first2 = B. R. | last3 = Rice | first3 = K. C. | doi=10.1016/s0091-3057(98)00040-9}} {{Navboxes| title = Pharmacodynamics | titlestyle = background:#ccccff | list1 ={{Ionotropic glutamate receptor modulators}}{{Monoamine reuptake inhibitors}}{{Sigma receptor modulators}} }}{{nervous-system-drug-stub}} 6 : Dopamine reuptake inhibitors|Dissociative drugs|NMDA receptor antagonists|Piperidines|Sigma agonists|Isothiocyanates |
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