“Fractional synthetic rate”的意思、由来-开放百科全书

A fractional synthetic rate (FSR) is the rate at which a precursor compound is incorporated into a product per unit of product mass.^[1] The metric has been used to estimate the rate at which proteins, lipids, and lipoproteins are synthesized within humans and other animals.^[1]^[2] The formula used to calculate the FSR from a stable isotope tracer experiment is:^[1]

1. ^¹²{{cite journal | vauthors = Foster DM, Barrett PH, Toffolo G, Beltz WF, Cobelli C | title = Estimating the fractional synthetic rate of plasma apolipoproteins and lipids from stable isotope data | journal = J. Lipid Res. | volume = 34 | issue = 12 | pages = 2193–2205 | year = 1993 | pmid = 8301238 | doi = | url = http://www.jlr.org/content/34/12/2193.full.pdf}}
2. ^{{cite journal | vauthors = Wilkinson DJ, Hossain T, Hill DS, Phillips BE, Crossland H, Williams J, Loughna P, Churchward-Venne TA, Breen L, Phillips SM, Etheridge T, Rathmacher JA, Smith K, Szewczyk NJ, Atherton PJ | title = Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism | journal = J. Physiol. | volume = 591 | issue = 11 | pages = 2911–2923 | date = June 2013 | pmid = 23551944 | pmc = 3690694 | doi = 10.1113/jphysiol.2013.253203 | url = https://core.ac.uk/download/files/80/20023706.pdf }}

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