| 词条 | Frederick National Laboratory for Cancer Research |
| 释义 |
The Frederick National Laboratory for Cancer Research (FNLCR) is a United States Federally Funded Research and Development Center (FFRDC) supported by the National Cancer Institute and managed by the private contractor Leidos Biomedical Research. The institution was originally established under the name Frederick Cancer Research and Development Center in 1972 as a component of President Richard Nixon's War on Cancer initiative. In 2012, the institution received a national laboratory designation and assumed its current name, becoming the only U.S. national laboratory exclusively dedicated to biomedical research. The campus in Frederick, Maryland also houses National Cancer Institute laboratories and administrative organizations, and is colloquially referred to as NCI-Frederick.[1][2] HistoryAs part of the 1971 War on Cancer initiative, Richard Nixon requested that the United States Army transfer land and buildings which were then part of Fort Detrick to the Department of Health and Human Services in order to support the research efforts of the National Cancer Institute. The new laboratory was established in 1972 under the name "Frederick Cancer Research and Development Center" and received a designation as a Federally Funded Research and Development Center in 1975. This organizational model, also used by Lawrence Livermore National Laboratory and Los Alamos National Laboratory among others, specifies a type of public-private partnership composed of an institution that is owned by the federal government but operated by a private contractor.[1] The laboratory was administratively reorganized in 1981, resulting in changing the name to "Frederick Cancer Research Center". In 2012, it was formally designated "Frederick National Laboratory for Cancer Research", becoming the first U.S. national laboratory owned by the Department of Health and Human Services and the only one exclusively dedicated to biomedical research.[1][2] (HHS has since also established the CMS Alliance to Modernize Healthcare in cooperation with the Centers for Medicare and Medicaid Services.[3]) The transition to redesignate FNLCR as a national laboratory was spearheaded by then-NCI director Harold Varmus.[4] Current operationsFNLCR currently operates a number of research programs and facilities designed to support National Institutes of Health research goals. FNLCR contains two pharmaceutical manufacturing facilities to support clinical trials run by the National Cancer Institute and the National Institute of Allergy and Infectious Diseases; manages a large collection of research samples, biological specimens, and mouse models used in cancer research; and hosts specific research projects such as the RAS Initiative, aimed at studying the biology of common oncogenes in the Ras subfamily, and the Nanotechnology Characterization Laboratory.[5] Since 1995, the contractor operating the facility has been Leidos Biomedical Research (formerly SAIC-Frederick).[1] That contract was renewed for ten years in 2008.[6] In 2015 the NCI began seeking applications for a new contract expected to be awarded in January 2017;[6] however, this search was suspended in September 2016.[7] NCI-FrederickIn addition to the FNLCR, the Frederick biomedical research campus also houses NCI facilities such as research laboratories, administrative organizations, and the separate NCI Center for Cancer Research. The facilities are collectively known as NCI-Frederick but are administratively distinct.[1][8] References1. ^1 2 3 4 {{cite journal|last1=Lombo|first1=Tania B.|title=What’s Happening in NCI’s Storied Labs to the North?|journal=NIH Catalyst|date=March 2013|volume=21|issue=2|url=https://irp.nih.gov/catalyst/v21i2/nci-campus-in-frederick|accessdate=21 November 2016}} {{coord|39.438761|-77.362607|type:landmark_globe:earth_region:US-MD|display=title}}2. ^1 {{cite web|title=History of the Frederick National Laboratory for Cancer Research|url=https://frederick.cancer.gov/About/History.aspx|website=Frederick National Laboratory for Cancer Research|accessdate=21 November 2016}} 3. ^{{cite web|title=Master Government List of Federally Funded R&D Centers|url=https://www.nsf.gov/statistics/ffrdclist/|website=National Science Foundation|accessdate=21 November 2016|date=June 2016}} 4. ^{{cite news|last1=Bin Han Ong|first1=Matthew|title=NCI National Lab’s Budget to Grow Over Its $299.2 Million FY2013 Level|url=http://cancerletter.com/articles/20140228_2/|accessdate=21 November 2016|work=The Cancer Letter|date=28 February 2014}} 5. ^{{cite web|title=About the Frederick National Laboratory for Cancer Research|url=https://frederick.cancer.gov/About/Default.aspx|website=Frederick National Laboratory for Cancer Research|accessdate=21 November 2016}} 6. ^1 {{cite news|last1=Carignan|first1=Sylvia|title=Frederick National Laboratory may choose new management|url=http://www.fredericknewspost.com/places/local/frederick_county/frederick/frederick-national-laboratory-may-choose-new-management/article_7e6878bd-ca2b-5add-a2b7-3addba8743ee.html|accessdate=21 November 2016|work=The Frederick News-Post|date=31 July 2015}} 7. ^{{cite news|last1=Carignan|first1=Sylvia|title=Frederick National Lab's future funding put on hold|url=http://www.fredericknewspost.com/news/health/frederick-national-lab-s-future-funding-put-on-hold/article_422aa236-4593-552d-ba20-9a39d5e22e8e.html|accessdate=21 November 2016|work=The Frederick News-Post|date=3 October 2016}} 8. ^{{cite web|title=Definition of NCI Organizations and Facilities in Frederick|url=https://ncifrederick.cancer.gov/About/AtAGlance.aspx|website=NCI at Frederick|accessdate=21 November 2016}} 3 : National Institutes of Health|Federally Funded Research and Development Centers|Laboratories in the United States |
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