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词条 GD-42
释义

  1. See also

  2. References

{{short description|Chemical compound}}{{Chembox
| Name = GD-42
| ImageFile = GD-42.svg
| IUPACName = 4,8-Dimethyl-3-oxa-5-thia-8-thionia-4-phosphadecane 4-oxide methyl sulfate
| OtherNames = Methylsulfomethylate
| Section1 = {{Chembox Identifiers
| CASNo = 2562-54-1
| ChemSpiderID = 144645
| PubChem = 164986
| SMILES = CCOP(=O)(C)SCC[S+](C)CC.COS(=O)(=O)[O-]
| StdInChI = InChI=1S/C8H20O2PS2.CH4O4S/c1-5-10-11(3,9)12-7-8-13(4)6-2;1-5-6(2,3)4/h5-8H2,1-4H3;1H3,(H,2,3,4)/q+1;/p-1
| StdInChIKey = AUACWHVUVIIDOR-UHFFFAOYSA-M
}}
| Section2 = {{Chembox Properties
| C=9|H=23|O=6|P=1|S=3
}}
}}

GD-42 (methylsulfomethylate) is an irreversible acetylcholinesterase inhibitor.[1][2] It has a positively charged sulfonium group.

See also

  • Armine (chemical)
  • Paraoxon
  • Ro 3-0419
  • Ro 3-0422
  • V-sub x

References

1. ^{{cite journal |last1=Danilov |first1=AF |last2=Kvitko |first2=IJ |last3=Lavrentieva |first3=VV |last4=Michelson |first4=MJ |last5=Porai-Koshits |first5=BA |last6=Rozhkova |first6=EK |last7=Shelkovnikov |first7=SA |title=Action of some bisquaternary derivatives of phthalic acids and related substances on neuromuscular transmission. |journal=British Journal of Pharmacology |date=April 1972 |volume=44 |issue=4 |pages=765–78 |pmid=4339387 |pmc=1665980}}
2. ^{{cite journal |last1=Danilov |first1=AF |last2=Ivanov |first2=YJ |last3=Michelson |first3=MJ |title=The influence of motor nerve tetanization on the effect of organophosphorus cholinesterase inhibitors on neuromuscular transmission. |journal=British Journal of Pharmacology |date=January 1976 |volume=56 |issue=1 |pages=115–23 |pmid=175873 |pmc=1666757}}
{{Acetylcholine metabolism and transport modulators}}{{Organic-compound-stub}}

4 : Acetylcholinesterase inhibitors|Phosphonothioates|Sulfonium compounds|Ethyl esters

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