| 词条 | Giovanni J. Ughi |
| 释义 |
| name = Giovanni J. Ughi | image = | caption = Giovanni J. Ughi | birth_date = | birth_place = Padova, Italy | residence = U.S. | nationality = Italian | field = Biomedical Optics | work_institutions = Harvard University | alma_mater = University of Padova; Katholieke Universiteit Leuven; Harvard Medical School; | known_for = optical coherence tomography; intravascular fluorescence; Image processing; | prizes = Bullock-Wellman Postdoctoral Fellowship {{small|(2014)}} – Harvard Medical School[1]Giovanni J. Ughi (born Padova, Italy), Italian engineer and scientist, is one of the inventors of multimodality Optical Coherence Tomography (OCT) and Laser-induced fluorescence molecular imaging, pioneering a first-in-man study of coronary arteries during his work at Massachusetts General Hospital.[2][3][4] The results of his work, combining two imaging technologies, may better identify dangerous coronary plaques, responsible for coronary artery disease and myocardial infarction.[5][6] He also was one of the pioneers of targeted molecular imaging of human atherosclerosis, determining the use of a FDA approved molecular agent (i.e., indocyanine green (ICG)-enhanced near-infrared fluorescence) that can illuminate high-risk features of human carotid atherosclerotic plaques[7] and other molecular agents for the identification of unhealed stents that are at higher risk of stent thrombosis.[8] Dr. Ughi also made significant contributions to the development of methods for the computer-based, automated analysis of Intracoronary optical coherence tomography (OCT) images, helping the widespread adoption of intracoronary OCT imaging technology.[9][10][11] He is recognized for the development of methods for the automatic quantification of stent characteristics on intracoronary optical coherence tomography images.[12] He authored over 40 papers in peer-reviewed scientific international journals.[13] References1. ^{{cite web |url=http://wellman.massgeneral.org/news-archive.htm |title=2014 Bullock-Wellman Fellowship Award Recipients |publisher=Wellman Center for Photomedicine |access-date=8 September 2016}} 2. ^{{cite web |url=https://www.tctmd.com/news/does-new-dual-modality-imaging-come-closer-uncovering-vulnerable-plaques |title=Does New Dual-Modality Imaging Come Closer to Uncovering Vulnerable Plaques? |last=Neale |first=Todd |publisher=Cardiovascular Research Foundation |date=11 March 2016 |website=TCTMD |access-date=13 September 2016}} 3. ^{{cite journal |vauthors= Psaltis PJ, Nicholls SJ |date=2016 |title=Imaging: Focusing light on the vulnerable plaque |journal= Nature Reviews Cardiology |volume=13 |issue=5|pages=253–255 |doi=10.1038/nrcardio.2016.53 |pmid=27087409 }} 4. ^{{cite journal |vauthors= Ughi GJ, Wang H, Gerbaud E, Gardecki JA, Fard AM, Hamidi E, Vacas-Jacques P, Rosenberg M, Jaffer FA, Tearney GJ |date=2016 |title=Clinical Characterization of Coronary Atherosclerosis With Dual-Modality OCT and Near-Infrared Autofluorescence Imaging |url=http://imaging.onlinejacc.org/article.aspx?articleid=2502012&resultClick=3 |journal= J Am Coll Cardiol Img |volume= 9|issue=11|pages= 1304–1314|doi=10.1016/j.jcmg.2015.11.020 |pmid= 26971006 |pmc=5010789}} 5. ^{{cite web |url=http://www.massgeneral.org/News/pressrelease.aspx?id=1908 |title=Combining two imaging technologies may better identify dangerous coronary plaques – Adding fluorescence imaging to OCT reveals biological, as well as structural information|publisher=Mass General News |access-date=7 September 2016}} 6. ^{{cite web |url=http://www.bioopticsworld.com/articles/2016/03/oct-fluorescence-imaging-pair-to-better-identify-heart-attack-prone-coronary-plaques.html |title=OCT, fluorescence imaging pair to better identify heart attack-prone coronary plaques |date=11 March 2016 |access-date=11 September 2016}} 7. ^{{cite journal |vauthors= Verjans JW, Osborn EA, Ughi GJ, Calfon Press MA, Hamidi E, Antoniadis AP, Papafaklis MI, Conrad MF, Libby P, Stone PH, Cambria RP, Tearney GJ, Jaffer FA|date=2016 |title=Targeted Near-Infrared Fluorescence Imaging of Atherosclerosis: Clinical and Intracoronary Evaluation of Indocyanine Green |url=http://imaging.onlinejacc.org/article.aspx?articleid=2544752&resultClick=3 |journal= J Am Coll Cardiol Img |volume=9 |issue=9|pages=1087–1095 |doi=10.1016/j.jcmg.2016.01.034 |pmid= 27544892 |pmc=5136528 }} 8. ^{{cite journal |vauthors= Hara T, Ughi GJ, McCarthy JR, Erdem SS, Mauskapf A, Lyon SC, Fard AM, Edelman ER, Tearney GJ, Jaffer FA |date=2015 |title=Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo |url=http://eurheartj.oxfordjournals.org/content/early/2015/12/17/eurheartj.ehv677 |journal= European Heart Journal |volume= 38|issue=6| pages= 447–455|doi=10.1093/eurheartj/ehv677 |pmid= 26685129 |pmc=5837565 }} 9. ^{{cite journal |authors= Ughi GJ, Van Dyck CJ, Adriaenssens T, Hoymans VY, Sinnaeve P, Timmermans JP, Desmet W, Vrints CJ, D'hooge J. |date=2014 |title=Automatic assessment of stent neointimal coverage by intravascular optical coherence tomography |journal= Eur Heart J Cardiovasc Imaging |volume=15 |issue=2| pages=195–200 |doi=10.1093/ehjci/jet134 |pmid= 23884965 }} 10. ^{{cite journal |vauthors= Ughi GJ, Adriaenssens T, Desmet W, D'hooge J |date=2012 |title=Fully automatic three-dimensional visualization of intravascular optical coherence tomography images |journal= Biomed Opt Express |volume=3 |issue=12|pages=3291–3303 |pmid= 23243578 |pmc = 3521298 |doi=10.1364/boe.3.003291}} 11. ^{{cite journal |vauthors= Ughi GJ, Adriaenssens T, Onsea K, Kayaert P, Dubois C, Sinnaeve P, Coosemans M, Desmet W, D'hooge J |date=2012 |title=Automatic segmentation of in-vivo intra-coronary optical coherence tomography images to assess stent strut apposition and coverage |journal= Int J Cardiovasc Imaging |volume=28 |issue=2| pages=229–241 |doi=10.1007/s10554-011-9824-3 |pmid= 21347593}} 12. ^{{cite web |url=http://www.octnews.org/articles/2552559/congratulations-to-giovanni-ughi-a-winner-of-the-s/ |title=winner of Optical Coherence Tomography Award |date=9 January 2011 |access-date=11 September 2016}} 13. ^{{cite web |url=https://scholar.google.com/citations?hl=en&user=Ps9yWKcAAAAJ |title=Giovanni J. Ughi, PhD | publisher=Google Scholar |access-date=20 April 2017}} External links
8 : Living people|Massachusetts General Hospital fellows|Harvard Medical School alumni|Harvard Medical School staff|Catholic University of Leuven alumni|University of Padua alumni|Biography (science and academia) articles by importance|Year of birth missing (living people) |
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