词条 | Glycerol 2-phosphate |
释义 |
| Name = Glycerol 2-phosphate | ImageFile = Glycerol 2-phosphate.svg | ImageSize = 200px | IUPACName = 1,3-Dihydroxypropan-2-yl dihydrogen phosphate | OtherNames = 1,2,3-Propanetriol, 2-(dihydrogen phosphate) Glycerol 2-phosphate β-Glycerophosphate β-Phosphoglycerol BGP | Section1 = {{Chembox Identifiers | CASNo = 17181-54-3 | PubChem = 2526 | EC_number = 241-228-2 | UNII = WWH06G87W6 | ChEMBL = 1232903 | ChemSpiderID = 2431 | ChEBI = 17270 | KEGG = C02979 | DrugBank = DB01779 | StdInChI=1S/C3H9O6P/c4-1-3(2-5)9-10(6,7)8/h3-5H,1-2H2,(H2,6,7,8) | StdInChIKey = DHCLVCXQIBBOPH-UHFFFAOYSA-N | SMILES = C(C(CO)OP(=O)(O)O)O | MeSHName = Beta-glycerophosphoric+acid | Section2 = {{Chembox Properties | C=3|H=9|O=6|P=1 | Appearance = | Density = | MeltingPt = | BoilingPt = | Section9 = {{Chembox Related | OtherFunction = Glycerol 1-phosphate Glycerol 3-phosphate | OtherFunction_label = organophosphates }} Glycerol 2-phosphate is a phosphoric ester of glycerol. It is more commonly known as β-glycerophosphate or BGP. Applicationsβ-Glycerophosphate is a classical serine-threonine phosphatase inhibitor. It is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition.[1][2] β-Glycerophosphate is also used to drive osteogenic differentiation of bone marrow stem cells in vitro.[3] β-Glycerophosphate is used to buffer M17 media for Lactococcus culture in recombinant protein expression.[4] Notes1. ^{{cite web|publisher=Sigma-Aldrich|title=β-Glycerophosphate disodium salt hydrate|url=https://www.sigmaaldrich.com/catalog/product/sigma/g6376|accessdate=2018-05-30}} {{Biochem-stub}}2. ^{{cite web|publisher=Thermo Fisher Scientific|title=Protease and Phosphatase Inhibitors|url=https://www.thermofisher.com/us/en/home/life-science/protein-biology/protein-biology-learning-center/protein-biology-resource-library/pierce-protein-methods/protease-phosphatase-inhibitors.html|accessdate=2018-05-30}} 3. ^{{cite journal|author=Langenbach & Handschel|year=2013|title=Effects of dexamethasone, ascorbic acid and β-glycerophosphate on the osteogenic differentiation of stem cells in vitro|journal=Stem Cell Research & Therapy|volume=4|issue=5|pages=117|url=https://stemcellres.biomedcentral.com/articles/10.1186/scrt328|doi=10.1186/scrt328|pmid=24073831|pmc=3854789}} 4. ^{{cite journal|author=Terzaghi & Sandine|year=1975|title=Improved medium for lactic streptococci and their bacteriophages|journal=Applied Microbiology|volume=29|issue=6|pages=807–813|url=http://aem.asm.org/content/29/6/807.short|pmid=16350018|pmc=187084}} 1 : Organophosphates |
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