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词条 Halocortolone
释义

  1. References

{{Drugbox
| Verifiedfields =
| Watchedfields =
| verifiedrevid =
| IUPAC_name = (6S,8S,9R,10S,11S,13S,14S,16R,17S)-9-Chloro-6,11-difluoro-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one
| image = Halocortolone.svg
| width =
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref =
| CAS_number = 24320-27-2
| CAS_supplemental =
| class = Corticosteroid; Glucocorticoid
| ATC_prefix =
| ATC_suffix =
| ATC_supplemental =
| PubChem = 20056980
| IUPHAR_ligand =
| DrugBank_Ref =
| DrugBank =
| ChemSpiderID_Ref =
| ChemSpiderID = 16736630
| UNII = Z9TL048W82
| KEGG =
| ChEBI =
| ChEMBL = 2106353
| C=22 | H=27 | Cl=1 | F=2 | O=3
| SMILES = C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@H]1C(=O)CO)C)F)Cl)C)F
| StdInChI_Ref =
| StdInChI = 1S/C22H27ClF2O3/c1-11-6-13-14-8-16(24)15-7-12(27)4-5-21(15,3)22(14,23)18(25)9-20(13,2)19(11)17(28)10-26/h4-5,7,11,13-14,16,18-19,26H,6,8-10H2,1-3H3/t11-,13+,14+,16+,18+,19-,20+,21+,22+/m1/s1
| StdInChIKey_Ref =
| StdInChIKey = MBRXSOUHUFBPQC-RFPWEZLHSA-N
| synonyms = 9α-Chloro-6α,11β-difluoro-21-hydroxy-16α-methylpregna-1,4-diene-3,20-dione
}}Halocortolone is a synthetic glucocorticoid corticosteroid which was never marketed.[1]

References

1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA618|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=618–}}
{{Glucocorticoid receptor modulators}}{{steroid-stub}}

6 : Alcohols|Chloroarenes|Diketones|Fluoroarenes|Glucocorticoids|Pregnanes

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