词条 | Hemoglobin J |
释义 |
Hemoglobin J is an abnormal hemoglobin, an alpha globin gene variant and present in various geographic locations. It was first reported in a black American family[1] in 1956. Later on reported from Indonsia, India, and other parts of the world. Hemoglobin J reported from Meerut India shows the mutation of 120th alanine to glutamic acid on alpha chain.[2] Hemoglobin J was also reported from Chhattisgarh, Central India as revealed by Lingojwar and coworkers in 2016.{{citation needed|date=September 2017}} References1. ^{{Cite journal|last=Thorup|first=O|date=1956|title=Hemoglobin j|journal=Science|doi=10.1126/science.123.3203.889|pmid=|access-date=13 April 2016|url=http://science.sciencemag.org/content/123/3203/889.full-text.pdf+html|volume=123|pages=889–890}} {{Gene-stub|date=February 2018}}2. ^{{Cite journal|last=Blackwell|first=R|date=May 10, 1974|title=Hemoglobin J Meerut: alpha120 Ala leads to Glu|journal=Biochim Biophys Acta|doi=10.1016/0005-2795(74)90060-9|pmid=4600474|volume=351|pages=7–12}} 1 : Blood disorders |
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