2000 U.S. Open may refer to:

• 2000 U.S. Open (golf), a major golf tournament
• 2000 US Open (tennis), a Grand Slam tennis tournament
• 2000 Lamar Hunt U.S. Open Cup, a soccer tournament for U.S. teams

• Bishop of wolverhampton
• Bishop of woolwich
• Bishop of worcester
• Bishop of wrexham
• Bishop of Wrocław
• Bishop of Wuerzburg
• Bishop of Wurzburg
• Bishop of Włocławek
• Bishop of Yokohama
• Bishop of Yucatan
• Bishop of Zamora
• Bishop of Zanzibar
• Bishop of Zips
• Bishop of Zmudz
• Bishop of Ávila
• Bishop of Éauze
• Bishop of Évora
• Bishop of Évry–Corbeil-Essonnes
• Bishop of Üxküll
• Bishop of Łomża
• Bishop of Żmudź
• Bishop Onell Soto
• Bishop Oscar Azarcon Solis
• Bishop Otter College
• Bishop Paiute Tribe