“Isomorph (gene)”的意思、由来-开放百科全书

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Isomorph (gene)

释义

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After Muller's classification was described as an isomorph, or gene mutation that expresses a nonsense point mutant with expression identical to the original allele.

Therefore, in respect of the relationships between the original and mutated genes it is difficult to ascertain the effects of dominanceness or/and recessiveness.^[1]^[2]

^[3]

Muller’s classification of mutant alleles

Category	Alternative function
Wild type	Referent gene expression, normal expression of parent allele
Amorph	Dysfunctional, with null expression
Hypomorph	Reduced or partially reduced gene activity
Hypermorph	Increased or partially increased parent gene activity
Neomorph	Novel function, compared to the new property
Antimorph	Interfering with gene activity
Isomorph	Expression identical to the original (parent) allele, mostly resulting from silent point mutations

References

1. ^{{cite book|editor=Lawrence E. |year=1999|title=Henderson's Dictionary of biological terms|publisher=Longman Group Ltd.|place= London|isbn= 0-582-22708-9}}
2. ^{{cite book|authors=Rieger R. Michaelis A., Green M. M. |year=1976|title= Glossary of genetics and cytogenetics: Classical and molecular|publisher= Springer-Verlag|place=Berlin - Heidelberg - New York|isbn=3-540-07668-9}}
3. ^http://www.its.caltech.edu/~bi190/SG4.pdf

1 : Mutation

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