| 词条 | Jane Grimwood |
| 释义 |
Jane Grimwood is a British microbiologist who later moved to the United States, settling in the state of Alabama. Early life and educationGrimwood was born in England.[1] Her father was a chemist, and she always wanted to be a scientist as a child.[1] Grimwood was awarded her B.Sc. and Ph.D. in Microbiology from the University of Leeds in the United Kingdom. She did her postdoctoral training at the University of Oxford, University of San Francisco and Dartmouth College. CareerHuman Genome ProjectGrimwood was an important part of the Human Genome Project effort, working from the Stanford Human Genome Center.[3] Grimwood stated, "I feel very lucky to have been a part of the Human Genome Project. It was arguably the best international collaborative project of our lifetime."[1] She and her team worked on sequencing and analyzing chromosomes 5, 16, and 19 -- "320 million base pairs . . . comprising more than 10% of the human genome." [2] They discovered that chromosome 19 has the highest gene density of any human chromosome, and were able to link certain genes on the chromosome to genetic diseases including insulin-resistant diabetes.[3][4] Current workSince the Human Genome Project finished in 2008, Grimwood has led a group of researchers who focus on sequencing and finishing a group of eukaryotic genomes that include fungi, plants, and vertebrates.[2] The lab focuses on the genomes of organisms relevant to the development of sustainable biofuels and global food security. Organisms they have worked on with this goal include "the American poplar, the hardy perennial grass, switchgrass and soybean." [1] Currently, she is the co-director of the Genome Sequencing Center and Faculty Investigator at the HudsonAlpha Institute for Biotechnology. In August 2015 the National Science Foundation awarded a $2.4 million grant jointly to a group of five researchers, including Grimwood.[5] The purpose of the grant is to further genomics research involving Upland cotton.[5][6]
The other four members of the grant team are Chris Saski, a Clemson University scientist, Jeffrey Chen from the University of Texas at Austin, David Stelly from Texas A&M, and Brian Scheffler from the U.S. Department of Agriculture.[7] References1. ^1 2 3 {{cite web|url=http://ftp.hudsonalpha.org/get-know-jane-grimwood|title=Get to Know: Jane Grimwood|work=hudsonalpha.org|accessdate=2 November 2015}} {{Authority control}}{{DEFAULTSORT:Grimwood, Jane}}2. ^1 2 {{cite web|url=http://www.hagsc.org/about/jgrimwood|title=Jane Grimwood|work=hagsc.org|accessdate=2 November 2015}} 3. ^{{Cite web|url=http://www.genomenewsnetwork.org/articles/2004/03/31/chromosomes.php|title=GNN - Two More Human Chromosomes Are Complete|website=www.genomenewsnetwork.org|access-date=2017-03-02}} 4. ^{{Cite journal|last=Grimwood|first=Jane|last2=Gordon|first2=Laurie A.|last3=Olsen|first3=Anne|last4=Terry|first4=Astrid|last5=Schmutz|first5=Jeremy|last6=Lamerdin|first6=Jane|last7=Hellsten|first7=Uffe|last8=Goodstein|first8=David|last9=Couronne|first9=Olivier|date=2004-04-01|title=The DNA sequence and biology of human chromosome 19|journal=Nature|volume=428|issue=6982|pages=529–535|doi=10.1038/nature02399|issn=1476-4687|pmid=15057824}} 5. ^1 {{cite web|url=http://thetandd.com/business/agriculture/cotton-map-clemson-scientist-shares-million-from-nsf-to-advance/article_2fc561a8-56bb-5ab6-9470-1efd3ca40bc1.html|title=COTTON ‘MAP’: Clemson scientist shares $2.4 million from NSF to advance genomic research|author=JIM MELVIN Clemson University|work=The Times and Democrat|accessdate=2 November 2015}} 6. ^1 {{cite web|url=http://www.waff.com/story/29639550/hudsonalpha-investigator-research-partners-receive-2m-to-sequence-upland-cotton-genome|title=HudsonAlpha investigator, research partners receive $2M to seque - WAFF-TV: News, Weather and Sports for Huntsville, AL|author=Liz Hurley|date=27 July 2015|work=waff.com|accessdate=2 November 2015}} 7. ^{{cite web|url=http://newsstand.clemson.edu/mediarelations/clemson-scientist-shares-2-4-million-from-nsf-to-advance-cotton-genomic-research/|title=Clemson scientist shares $2.4 million from NSF to advance cotton genomic research|work=clemson.edu|accessdate=2 November 2015}} 7 : British microbiologists|Living people|Year of birth missing (living people)|Women microbiologists|Alumni of the University of Leeds|21st-century American scientists|21st-century women scientists |
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