“2,3-dimethylmalate lyase”的意思、由来-开放百科全书

词条

2,3-dimethylmalate lyase

释义

References

{{enzyme
| Name = 2,3-dimethylmalate lyase
| EC_number = 4.1.3.32
| CAS_number = 73562-28-4
| IUBMB_EC_number = 4/1/3/32
| GO_code = 0047529
| image =
| width =
| caption =
}}

In enzymology, a 2,3-dimethylmalate lyase ({{EC number|4.1.3.32}}) is an enzyme that catalyzes the chemical reaction

(2R,3S)-2,3-dimethylmalate propanoate + pyruvate

Hence, this enzyme has one substrate, (2R,3S)-2,3-dimethylmalate, and two products, propanoate and pyruvate.

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming). Other names in common use include 2,3-dimethylmalate pyruvate-lyase, and (2R,3S)-2,3-dimethylmalate pyruvate-lyase. This enzyme participates in c5-branched dibasic acid metabolism.

References

{{cite journal |vauthors=Pirzer P, Lill U, Eggerer H | date = 1979 | title = Nicotinic acid metabolism. 2,3-Dimethylmalate lyase | journal = Hoppe-Seyler's Z. Physiol. Chem. | volume = 360 | pages = 1693–702 | pmid = 527937 | issue = 12 | doi = 10.1515/bchm2.1979.360.2.1693 }}
{{cite journal |vauthors=Alhapel A, Darley DJ, Wagener N, Eckel E, Elsner N, Pierik AJ | date = 2006 | title = Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 103 | pages = 12341–6 | pmid = 16894175 | doi = 10.1073/pnas.0601635103 | issue = 33 | pmc = 1562527 }}

2 : EC 4.1.3|Enzymes of unknown structure

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。