“2,8-Dihydroxyadenine”的意思、由来-开放百科全书

词条

2,8-Dihydroxyadenine

释义

References

{{chembox
| Verifiedfields = changed
| verifiedrevid = 477193857
| ImageFile=Dihydroxyadenine.png
| ImageSize=200px
| IUPACName=6-Amino-7,9-dihydro-1H-purine-2,8-dione
| OtherNames=
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 83302
| InChI = 1/C5H5N5O2/c6-2-1-3(9-4(11)7-1)10-5(12)8-2/h(H5,6,7,8,9,10,11,12)
| InChIKey = XFBOJHLYDJZYSP-UHFFFAOYAF
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C5H5N5O2/c6-2-1-3(9-4(11)7-1)10-5(12)8-2/h(H5,6,7,8,9,10,11,12)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = XFBOJHLYDJZYSP-UHFFFAOYSA-N
| CASNo_Ref = {{cascite|changed|??}}
| CASNo=30377-37-8
| PubChem=92268
| SMILES = O=C2N/C/1=N/C(=O)N\\C(=C\\1N2)N
| MeSHName=2,8-dihydroxyadenine
|Section2={{Chembox Properties
| Formula=C₅H₅N₅O₂
| MolarMass=167.126
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}

2,8-Dihydroxyadenine is a derivative of adenine which accumulates in 2,8 dihydroxy-adenine urolithiasis.

References

{{cite journal | title = Electrochemical behaviour of 2,8-dihydroxyadenine at a glassy carbon electrode | journal = Bioelectrochemistry | volume = 70| issue = 1| pages = 141–6| year = 2007| pmid = 16713382 | last1 = Diculescu | first1 = VC | last2 = Piedade | first2 = JA | last3 = Oliveira-Brett | first3 = AM | doi = 10.1016/j.bioelechem.2006.03.015}}
{{cite journal |vauthors=Taniguchi A, Tsuchida S, Kuno S, Mita M, Machida T, Ioritani N, Terai C, Yamanaka H, Kamatani N | title = Identification of two novel mutations in adenine phosphoribosyltransferase gene in patients with 2,8-dihydroxyadenine urolithiasis | journal = Nucleosides Nucleotides Nucleic Acids | volume = 23 | issue = 8–9 | pages = 1141–5 | year = 2004 | pmid = 15571218 | doi = 10.1081/NCN-200027393}}
{{cite journal |vauthors=Wilkinson H, Samuell C, Stower M | title = 2,8-Dihydroxyadenine renal stones in a 41-year-old man | journal = Ann Clin Biochem | volume = 41 | issue = Pt 2 | pages = 160–1 | year = 2004 | pmid = 15025810 | doi = 10.1258/000456304322880087}}

1 : Purines

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