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词条 2-C-Methylerythritol 4-phosphate
释义

  1. See also

  2. References

  3. External links

{{DISPLAYTITLE:2-C-Methylerythritol 4-phosphate}}{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 477197816
| Name=2-C-Methyl-D-erythritol 4-phosphate
| ImageFile=MEP.png
| ImageSize=
| IUPACName=(2R,3R)-2,3,4-trihydroxy-3-methylbutyl dihydrogen phosphate
| OtherNames=2-C-Methylerythritol 4-phosphate
|Section1={{Chembox Identifiers
| Abbreviations = MEP
| CASNo_Ref = {{cascite|changed|??}}
| CASNo=206440-72-4
| PubChem=443198
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 10246067
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 58262
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C5H13O7P/c1-5(8,3-6)4(7)2-12-13(9,10)11/h4,6-8H,2-3H2,1H3,(H2,9,10,11)/p-2/t4-,5+/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = XMWHRVNVKDKBRG-UHNVWZDZSA-L
| SMILES=CC(CO)(C(COP(=O)(O)O)O)O
|Section2={{Chembox Properties
| Formula=C5H13O7P
| MolarMass=216.126
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}

2-C-Methyl-D-erythritol 4-phosphate (MEP) is an intermediate on the MEP pathway (non-mevalonate pathway) of isoprenoid precursor biosynthesis.[1] It is the first committed metabolite on that pathway on the route to IPP and DMAPP.

See also

  • DXP reductoisomerase
  • MEP pathway (formerly known as the non-mevalonate pathway)
  • Fosmidomycin

References

1. ^{{cite journal |vauthors=Takahashi S, Kuzuyama T, Watanabe H, Seto H |title=A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue=17 |pages=9879–84 |year=1998 |pmid=9707569 |doi=10.1073/pnas.95.17.9879 |pmc=21430}}

External links

  • {{MeshName|2-C-methylerythritol+4-phosphate}}
{{DEFAULTSORT:Methylerythritol 4-phosphate, 2-C-}}{{biochem-stub}}

2 : Organophosphates|Monosaccharide derivatives

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