“2-furoyl-CoA dehydrogenase”的意思、由来-开放百科全书

词条

2-furoyl-CoA dehydrogenase

释义

References

{{enzyme
| Name = 2-furoyl-CoA dehydrogenase
| EC_number = 1.3.99.8
| CAS_number = 9068-18-2
| IUBMB_EC_number = 1/3/99/8
| GO_code = 0047542
| image =
| width =
| caption =
}}

In enzymology, a 2-furoyl-CoA dehydrogenase ({{EC number|1.3.99.8}}) is an enzyme that catalyzes the chemical reaction

2-furoyl-CoA + H₂O + acceptor S-(5-hydroxy-2-furoyl)-CoA + reduced acceptor

The 3 substrates of this enzyme are 2-furoyl-CoA, H₂O, and acceptor, whereas its two products are S-(5-hydroxy-2-furoyl)-CoA and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is 2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating). Other names in common use include furoyl-CoA hydroxylase, 2-furoyl coenzyme A hydroxylase, 2-furoyl coenzyme A dehydrogenase, and 2-furoyl-CoA:(acceptor) 5-oxidoreductase (hydroxylating). It employs one cofactor, copper.

References

{{cite journal |vauthors=Kitcher JP, Trudgill PW, Rees JS | date = 1972 | title = Purification and properties of 2-furoyl-coenzyme A hydroxylase from Pseudomonas putida F2 | journal = Biochem. J. | volume = 130 | pages = 121–32 | pmid = 4655411 | issue = 1 | pmc = 1174307 }}

3 : EC 1.3.99|Copper enzymes|Enzymes of unknown structure

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