| 词条 | 2-hydroxyphytanoyl-CoA lyase |
| 释义 |
|Name=2-hydroxyacyl-CoA lyase 1 |caption= |image= |width= |HGNCid=17856 |Symbol=HACL1 |AltSymbols=HPCL |EntrezGene=26061 |OMIM=604300 |RefSeq=NM_012260 |UniProt=Q9UJ83 |PDB= |ECnumber= |Chromosome=3 |Arm=p |Band=24.3 |LocusSupplementaryData= }}2-Hydroxyphytanoyl-CoA lyase is a peroxisomal enzyme involved in the catabolism of phytanoic acid by α-oxidation. It requires thiamine diphosphate (ThDP) as cofactor.[1] It is classified under EC number 4.1. References1. ^{{cite journal |vauthors=Foulon V, Antonenkov V, Croes K |title=Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue=18 |pages=10039–44 |year=1999 |pmid=10468558 |doi=10.1073/pnas.96.18.10039 |pmc=17838|display-authors=etal}} External links
1 : EC 4.1 |
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