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词条 2-oxo-acid reductase
释义

  1. References

{{enzyme
| Name = 2-oxo-acid reductase
| EC_number = 1.1.99.30
| CAS_number = 115299-99-5
| IUBMB_EC_number = 1/1/99/30
| GO_code =
| image =
| width =
| caption =
}}

In enzymology, a 2-oxo-acid reductase ({{EC number|1.1.99.30}}) is an enzyme that catalyzes the chemical reaction

a (2R)-hydroxy-carboxylate + acceptor a 2-oxo-carboxylate + reduced acceptor

Thus, the two substrates of this enzyme are (2R)-hydroxy-carboxylate and acceptor, whereas its two products are 2-oxo-carboxylate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (2R)-hydroxy-carboxylate:acceptor oxidoreductase. Other names in common use include (2R)-hydroxycarboxylate-viologen-oxidoreductase, HVOR, and 2-oxoacid reductase.

References

  • {{cite journal |vauthors=Trautwein T, Krauss F, Lottspeich F, Simon H | date = 1994 | title = The (2R)-hydroxycarboxylate-viologen-oxidoreductase from Proteus vulgaris is a molybdenum-containing iron-sulphur protein | journal = Eur. J. Biochem. | volume = 222 | pages = 1025–32 | pmid = 8026480 | doi = 10.1111/j.1432-1033.1994.tb18954.x | issue = 3 }}
  • {{cite journal |vauthors=Neumann S, Simon H | date = 1985 | title = On a non-pyridine nucleotide-dependent 2-oxoacid reductase of broad specificity from two Proteus species | journal = FEBS Lett. | volume = 167 | issue = 1 | pages = 29–32 | doi = 10.1016/0014-5793(84)80826-1 }}
{{Alcohol oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{1.1-enzyme-stub}}

2 : EC 1.1.99|Enzymes of unknown structure

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