“2-oxoadipate reductase”的意思、由来-开放百科全书

词条

2-oxoadipate reductase

释义

References

{{enzyme
| Name = 2-oxoadipate reductase
| EC_number = 1.1.1.172
| CAS_number = 61116-21-0
| IUBMB_EC_number = 1/1/1/172
| GO_code = 0047550
| image =
| width =
| caption =
}}

In enzymology, a 2-oxoadipate reductase ({{EC number|1.1.1.172}}) is an enzyme that catalyzes the chemical reaction

2-hydroxyadipate + NAD⁺ 2-oxoadipate + NADH + H⁺

Thus, the two substrates of this enzyme are 2-hydroxyadipate and NAD⁺, whereas its 3 products are 2-oxoadipate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 2-hydroxyadipate:NAD⁺ 2-oxidoreductase. Other names in common use include 2-ketoadipate reductase, alpha-ketoadipate reductase, and 2-ketoadipate reductase.

References

{{cite journal |vauthors=Suda T, Robinson JC, Fjellstedt TA | date = 1976 | title = Purification and properties of alpha-ketoadipate reductase, a newly discovered enzyme from human placenta | journal = Arch. Biochem. Biophys. | volume = 176 | pages = 610–20 | pmid = 185965 | doi = 10.1016/0003-9861(76)90205-8 | issue = 2 }}

3 : EC 1.1.1|NADH-dependent enzymes|Enzymes of unknown structure

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。